Eco-friendly polyethylene glycol (PEG-400): a green reaction medium for one-pot, four-component synthesis of novel asymmetrical bis-spirooxindole derivatives at room temperature

PEG-400 has been used as a green and biodegradable polymeric solvent for the one-pot, two-step, multi-component synthesis of novel asymmetrical bis-spirooxindole derivatives by the reaction of N-alkyl isatin, isatin derivatives, alkylmalonates and C–H activated carbonyl compounds in the presence of...

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Detalles Bibliográficos
Autores principales: Hasaninejad, Alireza, Beyrati, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077237/
https://www.ncbi.nlm.nih.gov/pubmed/35542580
http://dx.doi.org/10.1039/c7ra13133j
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author Hasaninejad, Alireza
Beyrati, Maryam
author_facet Hasaninejad, Alireza
Beyrati, Maryam
author_sort Hasaninejad, Alireza
collection PubMed
description PEG-400 has been used as a green and biodegradable polymeric solvent for the one-pot, two-step, multi-component synthesis of novel asymmetrical bis-spirooxindole derivatives by the reaction of N-alkyl isatin, isatin derivatives, alkylmalonates and C–H activated carbonyl compounds in the presence of K(2)CO(3) at room temperature. Using this procedure, all the products were obtained in good to excellent yields.
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spelling pubmed-90772372022-05-09 Eco-friendly polyethylene glycol (PEG-400): a green reaction medium for one-pot, four-component synthesis of novel asymmetrical bis-spirooxindole derivatives at room temperature Hasaninejad, Alireza Beyrati, Maryam RSC Adv Chemistry PEG-400 has been used as a green and biodegradable polymeric solvent for the one-pot, two-step, multi-component synthesis of novel asymmetrical bis-spirooxindole derivatives by the reaction of N-alkyl isatin, isatin derivatives, alkylmalonates and C–H activated carbonyl compounds in the presence of K(2)CO(3) at room temperature. Using this procedure, all the products were obtained in good to excellent yields. The Royal Society of Chemistry 2018-01-09 /pmc/articles/PMC9077237/ /pubmed/35542580 http://dx.doi.org/10.1039/c7ra13133j Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Hasaninejad, Alireza
Beyrati, Maryam
Eco-friendly polyethylene glycol (PEG-400): a green reaction medium for one-pot, four-component synthesis of novel asymmetrical bis-spirooxindole derivatives at room temperature
title Eco-friendly polyethylene glycol (PEG-400): a green reaction medium for one-pot, four-component synthesis of novel asymmetrical bis-spirooxindole derivatives at room temperature
title_full Eco-friendly polyethylene glycol (PEG-400): a green reaction medium for one-pot, four-component synthesis of novel asymmetrical bis-spirooxindole derivatives at room temperature
title_fullStr Eco-friendly polyethylene glycol (PEG-400): a green reaction medium for one-pot, four-component synthesis of novel asymmetrical bis-spirooxindole derivatives at room temperature
title_full_unstemmed Eco-friendly polyethylene glycol (PEG-400): a green reaction medium for one-pot, four-component synthesis of novel asymmetrical bis-spirooxindole derivatives at room temperature
title_short Eco-friendly polyethylene glycol (PEG-400): a green reaction medium for one-pot, four-component synthesis of novel asymmetrical bis-spirooxindole derivatives at room temperature
title_sort eco-friendly polyethylene glycol (peg-400): a green reaction medium for one-pot, four-component synthesis of novel asymmetrical bis-spirooxindole derivatives at room temperature
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077237/
https://www.ncbi.nlm.nih.gov/pubmed/35542580
http://dx.doi.org/10.1039/c7ra13133j
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AT beyratimaryam ecofriendlypolyethyleneglycolpeg400agreenreactionmediumforonepotfourcomponentsynthesisofnovelasymmetricalbisspirooxindolederivativesatroomtemperature

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