Cargando…

Periplocymarin alleviates pathological cardiac hypertrophy via inhibiting the JAK2/STAT3 signalling pathway

Pathological cardiac hypertrophy is the most important risk factor for developing chronic heart failure. Therefore, the discovery of novel agents for treating pathological cardiac hypertrophy remains urgent. In the present study, we examined the therapeutic effect and mechanism of periplocymarin (PM...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Cai‐lian, Liang, Sui, Ye, Meng‐nan, Cai, Wan‐jun, Chen, Miao, Hou, Yun‐long, Guo, Jun, Dai, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077305/ https://www.ncbi.nlm.nih.gov/pubmed/35365949 http://dx.doi.org/10.1111/jcmm.17267

Ejemplares similares

Periplocymarin Alleviates Doxorubicin-Induced Heart Failure and Excessive Accumulation of Ceramides
por: Yun, Weijing, et al.
Publicado: (2021)

Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway
por: Al-rasheed, Nouf M, et al.
Publicado: (2015)

Periplocymarin Plays an Efficacious Cardiotonic Role via Promoting Calcium Influx
por: Yun, Weijing, et al.
Publicado: (2020)

Periplocymarin Induced Colorectal Cancer Cells Apoptosis Via Impairing PI3K/AKT Pathway
por: Cheng, Yi, et al.
Publicado: (2021)

Improving cellular uptake and bioavailability of periplocymarin-linoleic acid prodrug by combining PEGylated liposome
por: Zhang, Huiyun, et al.
Publicado: (2022)

Octreotide-periplocymarin conjugate prodrug for improving targetability and anti-tumor efficiency: synthesis, in vitro and in vivo evaluation
por: Zhang, Hui-Yun, et al.
Publicado: (2016)

Dual targets of lethal apoptosis and protective autophagy in liver cancer with periplocymarin elicit a limited therapeutic effect
por: Hao, Yuanyuan, et al.
Publicado: (2023)

Fibroblast growth factor 18 alleviates stress-induced pathological cardiac hypertrophy in male mice
por: Chen, Gen, et al.
Publicado: (2023)

Astragaloside IV alleviates heart failure by promoting angiogenesis through the JAK-STAT3 pathway
por: Sui, Yan-Bo, et al.
Publicado: (2019)

Flavonoids Extraction from Propolis Attenuates Pathological Cardiac Hypertrophy through PI3K/AKT Signaling Pathway
por: Sun, Guang-wei, et al.
Publicado: (2016)

JAK/STAT pathway in pathology of rheumatoid arthritis (Review)
por: Ciobanu, Dana Alexandra, et al.
Publicado: (2020)

The Interaction of the IFNγ/JAK/STAT1 and JAK/STAT3 Signalling Pathways in EGFR-Mutated Lung Adenocarcinoma Cells
por: Han, Yaguang, et al.
Publicado: (2022)

FNDC5 attenuates obesity-induced cardiac hypertrophy by inactivating JAK2/STAT3-associated inflammation and oxidative stress
por: Geng, Zhi, et al.
Publicado: (2019)

Myricetin Alleviates Pathological Cardiac Hypertrophy via TRAF6/TAK1/MAPK and Nrf2 Signaling Pathway
por: Liao, Hai-han, et al.
Publicado: (2019)

Heat‐shock transcription factor 1 is critically involved in the ischaemia‐induced cardiac hypertrophy via JAK2/STAT3 pathway
por: Yuan, Lingyan, et al.
Publicado: (2018)

Hydrogen-rich saline mitigates pressure overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway
por: Wang, Chufeng, et al.
Publicado: (2020)

Loganin Inhibits Angiotensin II–Induced Cardiac Hypertrophy Through the JAK2/STAT3 and NF-κB Signaling Pathways
por: Xu, Jia-jia, et al.
Publicado: (2021)

JAK-STAT signaling in cardiomyogenesis of cardiac stem cells
por: Mohri, Tomomi, et al.
Publicado: (2012)

Gastrodin Inhibits Store-Operated Ca(2+) Entry and Alleviates Cardiac Hypertrophy
por: Zheng, Changbo, et al.
Publicado: (2017)

The Role of CD147 in Pathological Cardiac Hypertrophy Is Regulated by Glycosylation
por: Zhong, Fang-yuan, et al.
Publicado: (2022)

Inhibition of JAK-STAT Signaling Pathway Alleviates Age-Related Phenotypes in Tendon Stem/Progenitor Cells
por: Chen, Minhao, et al.
Publicado: (2021)

Functions of Autophagy in Pathological Cardiac Hypertrophy
por: Li, Zhenhua, et al.
Publicado: (2015)

VCP represses pathological cardiac hypertrophy
por: Zhou, Ning, et al.
Publicado: (2017)

Shuxie-1 Decoction Alleviated CUMS -Induced Liver Injury via IL-6/JAK2/STAT3 Signaling
por: Zhang, Mengting, et al.
Publicado: (2022)

JAKs and STATs in chemoresistance
por: Costa-Pereira, Ana P
Publicado: (2010)

JAK-STAT and feeding
por: Ladyman, Sharon R., et al.
Publicado: (2013)

CD9 exacerbates pathological cardiac hypertrophy through regulating GP130/STAT3 signaling pathway
por: Li, Yue, et al.
Publicado: (2023)

The role of local IL6/JAK2/STAT3 signaling in high glucose–induced podocyte hypertrophy
por: Jo, Hyung Ah, et al.
Publicado: (2016)

Does Transient Receptor Potential Vanilloid Type 1 Alleviate or Aggravate Pathological Myocardial Hypertrophy?
por: Yan, Qiqi, et al.
Publicado: (2021)

Celecoxib alleviates pathological cardiac hypertrophy and fibrosis via M1-like macrophage infiltration in neonatal mice
por: Zhao, Yanli, et al.
Publicado: (2021)

Mitochondria in Pathological Cardiac Hypertrophy Research and Therapy
por: Yang, Dan, et al.
Publicado: (2022)

Nicotinamide Riboside Alleviates Cardiac Dysfunction and Remodeling in Pressure Overload Cardiac Hypertrophy
por: Ma, Sai, et al.
Publicado: (2021)

Suppressor of IKKɛ is an essential negative regulator of pathological cardiac hypertrophy
por: Deng, Ke-Qiong, et al.
Publicado: (2016)

A JAK/STAT invasion
por: Wells, William A.
Publicado: (2002)

JAK-STAT and bone metabolism
por: Li, Jiliang
Publicado: (2013)

The Drosophila JAK-STAT pathway
por: Zeidler, Martin P, et al.
Publicado: (2013)

Evolution of the JAK-STAT pathway
por: Liongue, Clifford, et al.
Publicado: (2013)

The JAK-STAT pathway at 20
por: Darnell, Jr., James E.
Publicado: (2012)

JAK-STAT in lymphoproliferative disorders
por: Rabadan, Raul, et al.
Publicado: (2015)

An overview of JAK/STAT pathways and JAK inhibition in alopecia areata
por: Lensing, Maddison, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_g3bkn5ivvoli6v43k74cjqkb91