Passive immunization against phosphorylated tau improves features of Huntington's disease pathology

Huntington's disease is classically described as a neurodegenerative disorder of monogenic aetiology. The disease is characterized by an abnormal polyglutamine expansion in the huntingtin gene, which drives the toxicity of the mutated form of the protein. However, accumulation of the microtubul...

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Detalles Bibliográficos
Autores principales: Alpaugh, Melanie, Masnata, Maria, de Rus Jacquet, Aurelie, Lepinay, Eva, Denis, Hélèna L., Saint-Pierre, Martine, Davies, Peter, Planel, Emmanuel, Cicchetti, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077324/
https://www.ncbi.nlm.nih.gov/pubmed/35051614
http://dx.doi.org/10.1016/j.ymthe.2022.01.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077324/
https://www.ncbi.nlm.nih.gov/pubmed/35051614
http://dx.doi.org/10.1016/j.ymthe.2022.01.020

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