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Maleimidation of dextran and the application in designing a dextran–camptothecin conjugate
Camptothecin analogs, as commonly used chemotherapy drugs, usually have poor water solubility which has limited their use in the clinic. In order to improve the water-solubility of camptothecin, a new dextran derivative Dex-Mal was synthesized and used in designing a dextran–camptothecin conjugate w...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077361/ https://www.ncbi.nlm.nih.gov/pubmed/35541483 http://dx.doi.org/10.1039/c7ra12954h |