Molecular insights into the improved clinical performance of PEGylated interferon therapeutics: a molecular dynamics perspective

PEGylation is a widely adopted process to covalently attach a polyethylene glycol (PEG) polymer to a protein drug for the purpose of optimizing drug clinical performance. While the outcomes of PEGylation in imparting pharmacological advantages have been examined through experimental studies, the und...

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Detalles Bibliográficos
Autores principales: Xu, Dong, Smolin, Nikolai, Shaw, Rance K., Battey, Samuel R., Tao, Aoxiang, Huang, Yuying, Rahman, Shaikh Emdadur, Caylor, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077387/
https://www.ncbi.nlm.nih.gov/pubmed/35541455
http://dx.doi.org/10.1039/c7ra12480e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077387/
https://www.ncbi.nlm.nih.gov/pubmed/35541455
http://dx.doi.org/10.1039/c7ra12480e

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