Novel steroidal saponins with cytotoxic activities from the roots of Ophiopogon japonicus (L. f.) Ker-Gawl

Six new steroidal saponins (1–6) and one known steroidal saponin (7) were obtained from the roots of Ophiopogon japonicus (L. f.) Ker-Gawl. Their structures were determined by the detailed analysis of extensive nuclear magnetic resonance and mass spectroscopic data. The in vitro cytotoxic activities...

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Detalles Bibliográficos
Autores principales: Wu, Yan, Bi, Su-Xia, Huang, Zhen, Qi, Jin, Yu, Bo-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077439/
https://www.ncbi.nlm.nih.gov/pubmed/35541437
http://dx.doi.org/10.1039/c7ra12363a
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author Wu, Yan
Bi, Su-Xia
Huang, Zhen
Qi, Jin
Yu, Bo-Yang
author_facet Wu, Yan
Bi, Su-Xia
Huang, Zhen
Qi, Jin
Yu, Bo-Yang
author_sort Wu, Yan
collection PubMed
description Six new steroidal saponins (1–6) and one known steroidal saponin (7) were obtained from the roots of Ophiopogon japonicus (L. f.) Ker-Gawl. Their structures were determined by the detailed analysis of extensive nuclear magnetic resonance and mass spectroscopic data. The in vitro cytotoxic activities of these compounds against MDA-MB-435, HepG2 and A549 cell lines were also investigated.
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spelling pubmed-90774392022-05-09 Novel steroidal saponins with cytotoxic activities from the roots of Ophiopogon japonicus (L. f.) Ker-Gawl Wu, Yan Bi, Su-Xia Huang, Zhen Qi, Jin Yu, Bo-Yang RSC Adv Chemistry Six new steroidal saponins (1–6) and one known steroidal saponin (7) were obtained from the roots of Ophiopogon japonicus (L. f.) Ker-Gawl. Their structures were determined by the detailed analysis of extensive nuclear magnetic resonance and mass spectroscopic data. The in vitro cytotoxic activities of these compounds against MDA-MB-435, HepG2 and A549 cell lines were also investigated. The Royal Society of Chemistry 2018-01-11 /pmc/articles/PMC9077439/ /pubmed/35541437 http://dx.doi.org/10.1039/c7ra12363a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Wu, Yan
Bi, Su-Xia
Huang, Zhen
Qi, Jin
Yu, Bo-Yang
Novel steroidal saponins with cytotoxic activities from the roots of Ophiopogon japonicus (L. f.) Ker-Gawl
title Novel steroidal saponins with cytotoxic activities from the roots of Ophiopogon japonicus (L. f.) Ker-Gawl
title_full Novel steroidal saponins with cytotoxic activities from the roots of Ophiopogon japonicus (L. f.) Ker-Gawl
title_fullStr Novel steroidal saponins with cytotoxic activities from the roots of Ophiopogon japonicus (L. f.) Ker-Gawl
title_full_unstemmed Novel steroidal saponins with cytotoxic activities from the roots of Ophiopogon japonicus (L. f.) Ker-Gawl
title_short Novel steroidal saponins with cytotoxic activities from the roots of Ophiopogon japonicus (L. f.) Ker-Gawl
title_sort novel steroidal saponins with cytotoxic activities from the roots of ophiopogon japonicus (l. f.) ker-gawl
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077439/
https://www.ncbi.nlm.nih.gov/pubmed/35541437
http://dx.doi.org/10.1039/c7ra12363a
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