Mechanism studies of addition reactions between the pyrimidine type radicals and their 3′/5′ neighboring deoxyguanosines

To clarify the biologically significant sequence effect existing in the formation of the pyrimidine-type radicals induced DNA intrastrand cross-links, addition mechanisms between the uridine-5-methyl (˙U(CH(2))), 6-hydroxy-5,6-dihydrothymidine-5-yl (˙T(6OH)), and 6-hydroxy-5,6-dihydrocytidine-5-yl (...

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Detalles Bibliográficos
Autores principales: Wang, Shoushan, Zhang, Min, Liu, Peng, Xie, Shilei, Cheng, Faliang, Wang, Lishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077473/
https://www.ncbi.nlm.nih.gov/pubmed/35541474
http://dx.doi.org/10.1039/c7ra12713h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077473/
https://www.ncbi.nlm.nih.gov/pubmed/35541474
http://dx.doi.org/10.1039/c7ra12713h

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