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Mechanism studies of addition reactions between the pyrimidine type radicals and their 3′/5′ neighboring deoxyguanosines
To clarify the biologically significant sequence effect existing in the formation of the pyrimidine-type radicals induced DNA intrastrand cross-links, addition mechanisms between the uridine-5-methyl (˙U(CH(2))), 6-hydroxy-5,6-dihydrothymidine-5-yl (˙T(6OH)), and 6-hydroxy-5,6-dihydrocytidine-5-yl (...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077473/ https://www.ncbi.nlm.nih.gov/pubmed/35541474 http://dx.doi.org/10.1039/c7ra12713h |