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Asymmetric synthesis of polysubstituted chiral chromans via an organocatalytic oxa-Michael-nitro-Michael domino reaction

A catalytic asymmetric method for the synthesis of polysubstituted chromans via an oxa-Michael-nitro-Michael reaction has been developed. The squaramide-catalyzed domino reaction of 2-hydroxynitrostyrenes with trans-β-nitroolefins produced chiral chromans with excellent enantioselectivities (up to 9...

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Detalles Bibliográficos
Autores principales:	Tang, Cheng-Ke, Feng, Kai-Xiang, Xia, Ai-Bao, Li, Chen, Zheng, Ya-Yun, Xu, Zhen-Yuan, Xu, Dan-Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077565/ https://www.ncbi.nlm.nih.gov/pubmed/35541173 http://dx.doi.org/10.1039/c7ra13525d

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