Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones

A novel route for the synthesis of 2-arylated quinolines through a [5 + 1] annulation directly from 2-methylquinolines and diynones under catalyst-free and solvent-free conditions was disclosed. This synthetic process was atom-economic, with good tolerance of a broad range of functional groups, and...

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Detalles Bibliográficos
Autores principales: Zhao, Hai-Yuan, Wu, Fu-Song, Yang, Li, Liang, Ying, Cao, Xiao-Lin, Wang, Heng-Shan, Pan, Ying-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077778/
https://www.ncbi.nlm.nih.gov/pubmed/35539512
http://dx.doi.org/10.1039/c7ra12716b
Descripción
Sumario:A novel route for the synthesis of 2-arylated quinolines through a [5 + 1] annulation directly from 2-methylquinolines and diynones under catalyst-free and solvent-free conditions was disclosed. This synthetic process was atom-economic, with good tolerance of a broad range of functional groups, and with great practical worth.

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