Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones

A novel route for the synthesis of 2-arylated quinolines through a [5 + 1] annulation directly from 2-methylquinolines and diynones under catalyst-free and solvent-free conditions was disclosed. This synthetic process was atom-economic, with good tolerance of a broad range of functional groups, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Hai-Yuan, Wu, Fu-Song, Yang, Li, Liang, Ying, Cao, Xiao-Lin, Wang, Heng-Shan, Pan, Ying-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077778/
https://www.ncbi.nlm.nih.gov/pubmed/35539512
http://dx.doi.org/10.1039/c7ra12716b
_version_ 1784702185381036032
author Zhao, Hai-Yuan
Wu, Fu-Song
Yang, Li
Liang, Ying
Cao, Xiao-Lin
Wang, Heng-Shan
Pan, Ying-Ming
author_facet Zhao, Hai-Yuan
Wu, Fu-Song
Yang, Li
Liang, Ying
Cao, Xiao-Lin
Wang, Heng-Shan
Pan, Ying-Ming
author_sort Zhao, Hai-Yuan
collection PubMed
description A novel route for the synthesis of 2-arylated quinolines through a [5 + 1] annulation directly from 2-methylquinolines and diynones under catalyst-free and solvent-free conditions was disclosed. This synthetic process was atom-economic, with good tolerance of a broad range of functional groups, and with great practical worth.
format Online
Article
Text
id pubmed-9077778
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90777782022-05-09 Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones Zhao, Hai-Yuan Wu, Fu-Song Yang, Li Liang, Ying Cao, Xiao-Lin Wang, Heng-Shan Pan, Ying-Ming RSC Adv Chemistry A novel route for the synthesis of 2-arylated quinolines through a [5 + 1] annulation directly from 2-methylquinolines and diynones under catalyst-free and solvent-free conditions was disclosed. This synthetic process was atom-economic, with good tolerance of a broad range of functional groups, and with great practical worth. The Royal Society of Chemistry 2018-01-25 /pmc/articles/PMC9077778/ /pubmed/35539512 http://dx.doi.org/10.1039/c7ra12716b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Zhao, Hai-Yuan
Wu, Fu-Song
Yang, Li
Liang, Ying
Cao, Xiao-Lin
Wang, Heng-Shan
Pan, Ying-Ming
Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones
title Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones
title_full Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones
title_fullStr Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones
title_full_unstemmed Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones
title_short Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones
title_sort catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077778/
https://www.ncbi.nlm.nih.gov/pubmed/35539512
http://dx.doi.org/10.1039/c7ra12716b
work_keys_str_mv AT zhaohaiyuan catalystandsolventfreeapproachto2arylatedquinolinesvia51annulationof2methylquinolineswithdiynones
AT wufusong catalystandsolventfreeapproachto2arylatedquinolinesvia51annulationof2methylquinolineswithdiynones
AT yangli catalystandsolventfreeapproachto2arylatedquinolinesvia51annulationof2methylquinolineswithdiynones
AT liangying catalystandsolventfreeapproachto2arylatedquinolinesvia51annulationof2methylquinolineswithdiynones
AT caoxiaolin catalystandsolventfreeapproachto2arylatedquinolinesvia51annulationof2methylquinolineswithdiynones
AT wanghengshan catalystandsolventfreeapproachto2arylatedquinolinesvia51annulationof2methylquinolineswithdiynones
AT panyingming catalystandsolventfreeapproachto2arylatedquinolinesvia51annulationof2methylquinolineswithdiynones

Ejemplares similares