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Learning transmission dynamics modelling of COVID-19 using comomodels

The COVID-19 epidemic continues to rage in many parts of the world. In the UK alone, an array of mathematical models have played a prominent role in guiding policymaking. Whilst considerable pedagogical material exists for understanding the basics of transmission dynamics modelling, there is a subst...

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Detalles Bibliográficos
Autores principales: van der Vegt, Solveig A., Dai, Liangti, Bouros, Ioana, Farm, Hui Jia, Creswell, Richard, Dimdore-Miles, Oscar, Cazimoglu, Idil, Bajaj, Sumali, Hopkins, Lyle, Seiferth, David, Cooper, Fergus, Lei, Chon Lok, Gavaghan, David, Lambert, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077823/
https://www.ncbi.nlm.nih.gov/pubmed/35537550
http://dx.doi.org/10.1016/j.mbs.2022.108824
Descripción
Sumario:The COVID-19 epidemic continues to rage in many parts of the world. In the UK alone, an array of mathematical models have played a prominent role in guiding policymaking. Whilst considerable pedagogical material exists for understanding the basics of transmission dynamics modelling, there is a substantial gap between the relatively simple models used for exposition of the theory and those used in practice to model the transmission dynamics of COVID-19. Understanding these models requires considerable prerequisite knowledge and presents challenges to those new to the field of epidemiological modelling. In this paper, we introduce an open-source R package, comomodels, which can be used to understand the complexities of modelling the transmission dynamics of COVID-19 through a series of differential equation models. Alongside the base package, we describe a host of learning resources, including detailed tutorials and an interactive web-based interface allowing dynamic investigation of the model properties. We then use comomodels to illustrate three key lessons in the transmission of COVID-19 within R Markdown vignettes.