Cargando…

Learning transmission dynamics modelling of COVID-19 using comomodels

The COVID-19 epidemic continues to rage in many parts of the world. In the UK alone, an array of mathematical models have played a prominent role in guiding policymaking. Whilst considerable pedagogical material exists for understanding the basics of transmission dynamics modelling, there is a subst...

Descripción completa

Detalles Bibliográficos
Autores principales: van der Vegt, Solveig A., Dai, Liangti, Bouros, Ioana, Farm, Hui Jia, Creswell, Richard, Dimdore-Miles, Oscar, Cazimoglu, Idil, Bajaj, Sumali, Hopkins, Lyle, Seiferth, David, Cooper, Fergus, Lei, Chon Lok, Gavaghan, David, Lambert, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077823/
https://www.ncbi.nlm.nih.gov/pubmed/35537550
http://dx.doi.org/10.1016/j.mbs.2022.108824
_version_ 1784702195843727360
author van der Vegt, Solveig A.
Dai, Liangti
Bouros, Ioana
Farm, Hui Jia
Creswell, Richard
Dimdore-Miles, Oscar
Cazimoglu, Idil
Bajaj, Sumali
Hopkins, Lyle
Seiferth, David
Cooper, Fergus
Lei, Chon Lok
Gavaghan, David
Lambert, Ben
author_facet van der Vegt, Solveig A.
Dai, Liangti
Bouros, Ioana
Farm, Hui Jia
Creswell, Richard
Dimdore-Miles, Oscar
Cazimoglu, Idil
Bajaj, Sumali
Hopkins, Lyle
Seiferth, David
Cooper, Fergus
Lei, Chon Lok
Gavaghan, David
Lambert, Ben
author_sort van der Vegt, Solveig A.
collection PubMed
description The COVID-19 epidemic continues to rage in many parts of the world. In the UK alone, an array of mathematical models have played a prominent role in guiding policymaking. Whilst considerable pedagogical material exists for understanding the basics of transmission dynamics modelling, there is a substantial gap between the relatively simple models used for exposition of the theory and those used in practice to model the transmission dynamics of COVID-19. Understanding these models requires considerable prerequisite knowledge and presents challenges to those new to the field of epidemiological modelling. In this paper, we introduce an open-source R package, comomodels, which can be used to understand the complexities of modelling the transmission dynamics of COVID-19 through a series of differential equation models. Alongside the base package, we describe a host of learning resources, including detailed tutorials and an interactive web-based interface allowing dynamic investigation of the model properties. We then use comomodels to illustrate three key lessons in the transmission of COVID-19 within R Markdown vignettes.
format Online
Article
Text
id pubmed-9077823
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Authors. Published by Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-90778232022-05-09 Learning transmission dynamics modelling of COVID-19 using comomodels van der Vegt, Solveig A. Dai, Liangti Bouros, Ioana Farm, Hui Jia Creswell, Richard Dimdore-Miles, Oscar Cazimoglu, Idil Bajaj, Sumali Hopkins, Lyle Seiferth, David Cooper, Fergus Lei, Chon Lok Gavaghan, David Lambert, Ben Math Biosci Original Research Article The COVID-19 epidemic continues to rage in many parts of the world. In the UK alone, an array of mathematical models have played a prominent role in guiding policymaking. Whilst considerable pedagogical material exists for understanding the basics of transmission dynamics modelling, there is a substantial gap between the relatively simple models used for exposition of the theory and those used in practice to model the transmission dynamics of COVID-19. Understanding these models requires considerable prerequisite knowledge and presents challenges to those new to the field of epidemiological modelling. In this paper, we introduce an open-source R package, comomodels, which can be used to understand the complexities of modelling the transmission dynamics of COVID-19 through a series of differential equation models. Alongside the base package, we describe a host of learning resources, including detailed tutorials and an interactive web-based interface allowing dynamic investigation of the model properties. We then use comomodels to illustrate three key lessons in the transmission of COVID-19 within R Markdown vignettes. The Authors. Published by Elsevier Inc. 2022-07 2022-05-07 /pmc/articles/PMC9077823/ /pubmed/35537550 http://dx.doi.org/10.1016/j.mbs.2022.108824 Text en © 2022 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Research Article
van der Vegt, Solveig A.
Dai, Liangti
Bouros, Ioana
Farm, Hui Jia
Creswell, Richard
Dimdore-Miles, Oscar
Cazimoglu, Idil
Bajaj, Sumali
Hopkins, Lyle
Seiferth, David
Cooper, Fergus
Lei, Chon Lok
Gavaghan, David
Lambert, Ben
Learning transmission dynamics modelling of COVID-19 using comomodels
title Learning transmission dynamics modelling of COVID-19 using comomodels
title_full Learning transmission dynamics modelling of COVID-19 using comomodels
title_fullStr Learning transmission dynamics modelling of COVID-19 using comomodels
title_full_unstemmed Learning transmission dynamics modelling of COVID-19 using comomodels
title_short Learning transmission dynamics modelling of COVID-19 using comomodels
title_sort learning transmission dynamics modelling of covid-19 using comomodels
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077823/
https://www.ncbi.nlm.nih.gov/pubmed/35537550
http://dx.doi.org/10.1016/j.mbs.2022.108824
work_keys_str_mv AT vandervegtsolveiga learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT dailiangti learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT bourosioana learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT farmhuijia learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT creswellrichard learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT dimdoremilesoscar learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT cazimogluidil learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT bajajsumali learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT hopkinslyle learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT seiferthdavid learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT cooperfergus learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT leichonlok learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT gavaghandavid learningtransmissiondynamicsmodellingofcovid19usingcomomodels
AT lambertben learningtransmissiondynamicsmodellingofcovid19usingcomomodels