The circular RNA circHMGB2 drives immunosuppression and anti-PD-1 resistance in lung adenocarcinomas and squamous cell carcinomas via the miR-181a-5p/CARM1 axis

BACKGROUND: Previous studies have confirmed the oncogenic role of HMGB2 in various cancers, but the biological functions of HMGB2-derived circRNAs remain unknown. Thus, we intended to investigate the potential role of HMGB2-derived circRNAs in lung adenocarcinomas (LUAD) and squamous cell carcinomas...

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Detalles Bibliográficos
Autores principales: Zhang, Ling-Xian, Gao, Jian, Long, Xiang, Zhang, Peng-Fei, Yang, Xin, Zhu, Shu-Qiang, Pei, Xu, Qiu, Bai-Quan, Chen, Shi-Wei, Lu, Feng, Lin, Kun, Xu, Jian Jun, Wu, Yong-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077876/
https://www.ncbi.nlm.nih.gov/pubmed/35525959
http://dx.doi.org/10.1186/s12943-022-01586-w

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