Antiallodynic effects of KDS2010, a novel MAO-B inhibitor, via ROS-GABA inhibitory transmission in a paclitaxel-induced tactile hypersensitivity model

Monoamine oxidase (MAO) inhibitors have been investigated for the treatment of neuropathic pain. Here, we assessed the antiallodynic effects of a novel MAO-B inhibitor, KDS2010, on paclitaxel (PTX)-induced mechanical hypersensitivity. Oral administration of KDS2010 effectively relieved PTX-induced m...

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Detalles Bibliográficos
Autores principales: Park, Su Eun, Neupane, Chiranjivi, Noh, Chan, Sharma, Ramesh, Shin, Hyun Jin, Pham, Thuy Linh, Lee, Gyu-Seung, Park, Ki Duk, Lee, C. Justin, Kang, Dong-Wook, Lee, So Yeong, Kim, Hyun-Woo, Park, Jin Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078011/
https://www.ncbi.nlm.nih.gov/pubmed/35526002
http://dx.doi.org/10.1186/s13041-022-00924-9

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