Direct C–H functionalization of difluoroboron dipyrromethenes (BODIPYs) at β-position by iodonium salts

A copper-catalyzed direct C–H arylation or vinylation of BODIPYs at the β-position by iodonium salts has been developed, which provides facile access to a variety of mono-substituted BODIPY dyes. Interestingly, β-styryl BODIPY compound 9b exhibits apparent cytotoxicity after laser irradiation, which...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Wenming, Xiang, Huaijiang, Peng, Chengyuan, Musha, Zulipali, Chen, Jingjing, Li, Xin, Huang, Ruimin, Hu, Youhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078099/
https://www.ncbi.nlm.nih.gov/pubmed/35542398
http://dx.doi.org/10.1039/c7ra13070h
Descripción
Sumario:A copper-catalyzed direct C–H arylation or vinylation of BODIPYs at the β-position by iodonium salts has been developed, which provides facile access to a variety of mono-substituted BODIPY dyes. Interestingly, β-styryl BODIPY compound 9b exhibits apparent cytotoxicity after laser irradiation, which has great potential for photodynamic therapy.

Ejemplares similares