Menaquinone biosynthesis inhibition: a review of advancements toward a new antibiotic mechanism

Menaquinone is essential in electron transport and ATP generation in all Gram-positive, and anaerobically respiring Gram-negative bacteria. By inhibiting menaquinone production in target organisms, bactericidal action can be achieved irrespective of the organisms' growth phase. This pathway is...

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Detalles Bibliográficos
Autores principales: Boersch, M., Rudrawar, S., Grant, G., Zunk, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078190/
https://www.ncbi.nlm.nih.gov/pubmed/35542397
http://dx.doi.org/10.1039/c7ra12950e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078190/
https://www.ncbi.nlm.nih.gov/pubmed/35542397
http://dx.doi.org/10.1039/c7ra12950e

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