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Prevalence and Risk Factors of Abnormal Carotid Artery in Young Adults without Overt Cardiovascular Disease
OBJECTIVE: The current study was to evaluate the prevalence of increased carotid artery intimal-medial thickness (IMT) and carotid plaque in young individuals and factors associated with increased IMT and carotid plaque were also assessed. METHODS: Individuals between 18 and 44 years old who underwe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078336/ https://www.ncbi.nlm.nih.gov/pubmed/35535143 http://dx.doi.org/10.2147/IJGM.S360437 |
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author | Teng, Yunjie Wang, Kaiyang Fan, Xue Yang, Xiaoping |
author_facet | Teng, Yunjie Wang, Kaiyang Fan, Xue Yang, Xiaoping |
author_sort | Teng, Yunjie |
collection | PubMed |
description | OBJECTIVE: The current study was to evaluate the prevalence of increased carotid artery intimal-medial thickness (IMT) and carotid plaque in young individuals and factors associated with increased IMT and carotid plaque were also assessed. METHODS: Individuals between 18 and 44 years old who underwent an annual health examination and without cardiovascular disease were included. The value of IMT ≥0.1 cm was defined as increased IMT and IMT ≥0.15 cm was defined as carotid plaque. Based on the IMT, participants were divided into normal and abnormal groups. RESULTS: A total of 551 individuals were included and the mean age was 38.9 years old, with women accounting for 32.5% (n=179) and 238 (43.2%) individuals with abnormal IMT. Those with abnormal IMT was older, more likely to be male and smoking, had higher blood pressure (BP) and body mass index (BMI). Individuals with abnormal MIT also had worse lipid profiles, higher serum levels of fasting plasma glucose (FPG), HbA1c, homocysteine, and uric acid. Age, male sex, elevated systolic and diastolic BP, BMI, HbA1c, FPG, triglyceride, total cholesterol, LDL-C, homocysteine, and uric acid were positively correlated with IMT, while HDL-C was negatively correlated with IMT. Factors associated with increased IMT and carotid plaque included age, male sex, BMI, triglyceride, LDL-C, homocysteine, uric acid, and smoking. CONCLUSION: Among apparent healthy young individuals, the prevalence of increased IMT was high and there were several factors associated with increased IMT. Further studies are needed to evaluate how to be better in preventing the development of subclinical atherosclerosis among young individuals. |
format | Online Article Text |
id | pubmed-9078336 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-90783362022-05-08 Prevalence and Risk Factors of Abnormal Carotid Artery in Young Adults without Overt Cardiovascular Disease Teng, Yunjie Wang, Kaiyang Fan, Xue Yang, Xiaoping Int J Gen Med Original Research OBJECTIVE: The current study was to evaluate the prevalence of increased carotid artery intimal-medial thickness (IMT) and carotid plaque in young individuals and factors associated with increased IMT and carotid plaque were also assessed. METHODS: Individuals between 18 and 44 years old who underwent an annual health examination and without cardiovascular disease were included. The value of IMT ≥0.1 cm was defined as increased IMT and IMT ≥0.15 cm was defined as carotid plaque. Based on the IMT, participants were divided into normal and abnormal groups. RESULTS: A total of 551 individuals were included and the mean age was 38.9 years old, with women accounting for 32.5% (n=179) and 238 (43.2%) individuals with abnormal IMT. Those with abnormal IMT was older, more likely to be male and smoking, had higher blood pressure (BP) and body mass index (BMI). Individuals with abnormal MIT also had worse lipid profiles, higher serum levels of fasting plasma glucose (FPG), HbA1c, homocysteine, and uric acid. Age, male sex, elevated systolic and diastolic BP, BMI, HbA1c, FPG, triglyceride, total cholesterol, LDL-C, homocysteine, and uric acid were positively correlated with IMT, while HDL-C was negatively correlated with IMT. Factors associated with increased IMT and carotid plaque included age, male sex, BMI, triglyceride, LDL-C, homocysteine, uric acid, and smoking. CONCLUSION: Among apparent healthy young individuals, the prevalence of increased IMT was high and there were several factors associated with increased IMT. Further studies are needed to evaluate how to be better in preventing the development of subclinical atherosclerosis among young individuals. Dove 2022-05-03 /pmc/articles/PMC9078336/ /pubmed/35535143 http://dx.doi.org/10.2147/IJGM.S360437 Text en © 2022 Teng et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Teng, Yunjie Wang, Kaiyang Fan, Xue Yang, Xiaoping Prevalence and Risk Factors of Abnormal Carotid Artery in Young Adults without Overt Cardiovascular Disease |
title | Prevalence and Risk Factors of Abnormal Carotid Artery in Young Adults without Overt Cardiovascular Disease |
title_full | Prevalence and Risk Factors of Abnormal Carotid Artery in Young Adults without Overt Cardiovascular Disease |
title_fullStr | Prevalence and Risk Factors of Abnormal Carotid Artery in Young Adults without Overt Cardiovascular Disease |
title_full_unstemmed | Prevalence and Risk Factors of Abnormal Carotid Artery in Young Adults without Overt Cardiovascular Disease |
title_short | Prevalence and Risk Factors of Abnormal Carotid Artery in Young Adults without Overt Cardiovascular Disease |
title_sort | prevalence and risk factors of abnormal carotid artery in young adults without overt cardiovascular disease |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078336/ https://www.ncbi.nlm.nih.gov/pubmed/35535143 http://dx.doi.org/10.2147/IJGM.S360437 |
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