Efficient synthesis of ether phosphonates using trichloroacetimidate and acetate coupling methods

A series of ether phosphonates have been prepared by trichloroacetimidate and acetate coupling methods. Trichloroacetimidates or acetates were treated with primary and secondary alcohols as O-nucleophiles in the presence of catalytic TMSOTf to afford 21 examples of diethyl alkyloxy(substitutedphenyl...

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Detalles Bibliográficos
Autores principales: Fathalla, Walid., Ali, Ibrahim. A. I., Pazdera, Pavel.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078406/
https://www.ncbi.nlm.nih.gov/pubmed/35539144
http://dx.doi.org/10.1039/c8ra00702k
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author Fathalla, Walid.
Ali, Ibrahim. A. I.
Pazdera, Pavel.
author_facet Fathalla, Walid.
Ali, Ibrahim. A. I.
Pazdera, Pavel.
author_sort Fathalla, Walid.
collection PubMed
description A series of ether phosphonates have been prepared by trichloroacetimidate and acetate coupling methods. Trichloroacetimidates or acetates were treated with primary and secondary alcohols as O-nucleophiles in the presence of catalytic TMSOTf to afford 21 examples of diethyl alkyloxy(substitutedphenyl)methyl phosphonates via C–O bond formation in 55–90% yields and short reaction time.
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spelling pubmed-90784062022-05-09 Efficient synthesis of ether phosphonates using trichloroacetimidate and acetate coupling methods Fathalla, Walid. Ali, Ibrahim. A. I. Pazdera, Pavel. RSC Adv Chemistry A series of ether phosphonates have been prepared by trichloroacetimidate and acetate coupling methods. Trichloroacetimidates or acetates were treated with primary and secondary alcohols as O-nucleophiles in the presence of catalytic TMSOTf to afford 21 examples of diethyl alkyloxy(substitutedphenyl)methyl phosphonates via C–O bond formation in 55–90% yields and short reaction time. The Royal Society of Chemistry 2018-02-15 /pmc/articles/PMC9078406/ /pubmed/35539144 http://dx.doi.org/10.1039/c8ra00702k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Fathalla, Walid.
Ali, Ibrahim. A. I.
Pazdera, Pavel.
Efficient synthesis of ether phosphonates using trichloroacetimidate and acetate coupling methods
title Efficient synthesis of ether phosphonates using trichloroacetimidate and acetate coupling methods
title_full Efficient synthesis of ether phosphonates using trichloroacetimidate and acetate coupling methods
title_fullStr Efficient synthesis of ether phosphonates using trichloroacetimidate and acetate coupling methods
title_full_unstemmed Efficient synthesis of ether phosphonates using trichloroacetimidate and acetate coupling methods
title_short Efficient synthesis of ether phosphonates using trichloroacetimidate and acetate coupling methods
title_sort efficient synthesis of ether phosphonates using trichloroacetimidate and acetate coupling methods
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078406/
https://www.ncbi.nlm.nih.gov/pubmed/35539144
http://dx.doi.org/10.1039/c8ra00702k
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