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Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices

Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter, which enables clear identification of the distributions o...

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Detalles Bibliográficos
Autores principales: Kim, Jae Young, Seo, Eun Seok, Lim, Hee Jin, Kim, Hyunmin, Park, Ji-Won, Shin, Hyeon Ho, Lim, Dong-Kwon, Moon, Dae Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078475/
https://www.ncbi.nlm.nih.gov/pubmed/35541999
http://dx.doi.org/10.1039/c8ra00038g
Descripción
Sumario:Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter, which enables clear identification of the distributions of monoacylglycerol, adenine, cholesterol, sphingosine and ceramide.