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Metabolism of five diterpenoid lactones from Dioscorea bulbifera tubers in zebrafish

Diterpenoid lactones (DLs) have been reported to be the main hepatotoxic constituents in Dioscorea bulbifera tubers (DBT), a traditional Chinese medicinal herb. The acquisition of early information regarding its metabolism is critical for evaluating the potential hepatotoxicity of DLs. We investigat...

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Detalles Bibliográficos
Autores principales: Shi, Wei, Ling, Jie, Jiang, Li-Long, Zhao, Dong-Sheng, Wang, Ling-Li, Wu, Zi-Tian, Li, Ping, Wei, Ying-Jie, Li, Hui-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078502/
https://www.ncbi.nlm.nih.gov/pubmed/35539098
http://dx.doi.org/10.1039/c7ra12910f