A UPLC-MS/MS method for simultaneous quantification of pairs of oleanene- and ursane-type triterpenoid saponins and their major metabolites in mice plasma and its application to a comparative pharmacokinetic study

Ilexhainanoside D (IhD) and Ilexsaponin A(1) (IsA) are a pair of oleanene- and ursane-type triterpenoid saponins, which are also the main bioactive pharmaceutical ingredients of Ilex hainanensis Merr. with great potential to treat non-alcoholic fatty liver disease (NAFLD). The pharmacokinetics of fo...

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Detalles Bibliográficos
Autores principales: Zhao, Wenwen, Liu, Zongyang, Guo, Weiwei, Luo, Kui, Yang, Jie, Gao, Wei, Wu, Xia, Chen, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078533/
https://www.ncbi.nlm.nih.gov/pubmed/35539862
http://dx.doi.org/10.1039/c8ra00739j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078533/
https://www.ncbi.nlm.nih.gov/pubmed/35539862
http://dx.doi.org/10.1039/c8ra00739j

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