Cargando…

A UPLC-MS/MS method for simultaneous quantification of pairs of oleanene- and ursane-type triterpenoid saponins and their major metabolites in mice plasma and its application to a comparative pharmacokinetic study

Ilexhainanoside D (IhD) and Ilexsaponin A(1) (IsA) are a pair of oleanene- and ursane-type triterpenoid saponins, which are also the main bioactive pharmaceutical ingredients of Ilex hainanensis Merr. with great potential to treat non-alcoholic fatty liver disease (NAFLD). The pharmacokinetics of fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Wenwen, Liu, Zongyang, Guo, Weiwei, Luo, Kui, Yang, Jie, Gao, Wei, Wu, Xia, Chen, Xiaoqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078533/ https://www.ncbi.nlm.nih.gov/pubmed/35539862 http://dx.doi.org/10.1039/c8ra00739j

Ejemplares similares

Simultaneous Determination and Quantification of Triterpene Saponins from Camellia sinensis Seeds Using UPLC-PDA-QTOF-MS/MS
por: Wu, Xuejin, et al.
Publicado: (2019)

Comparative pharmacokinetic analysis of raw and steamed Panax notoginseng roots in rats by UPLC-MS/MS for simultaneously quantifying seven saponins
por: Dong, Jiajia, et al.
Publicado: (2021)

Characterization and Quantification of Polyphenols and Triterpenoids in Thinned Young Fruits of Ten Pear Varieties by UPLC-Q TRAP-MS/MS
por: Sun, Liqiong, et al.
Publicado: (2019)

Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS
por: Wu, Di, et al.
Publicado: (2018)

Quantification of Lappaconitine in Mouse Blood by UPLC-MS/MS and Its Application to a Pharmacokinetic Study
por: Chen, Fan, et al.
Publicado: (2019)

An UPLC-MS/MS Method for Simultaneous Quantification of the Components of Shenyanyihao Oral Solution in Rat Plasma
por: Jiang, Chunbo, et al.
Publicado: (2020)

Pharmacokinetics and metabolism of icaritin in rats by UPLC‐MS/MS
por: Huang, Zhen‐Wu, et al.
Publicado: (2019)

Simultaneous Determination of 11 Compounds in Gualou Guizhi Granule and Pharmacokinetics Study by UPLC-MS/MS
por: Sun, Chengtao, et al.
Publicado: (2017)

Simultaneous determination of cis- and trans-palmitoleic acid in rat serum by UPLC–MS/MS
por: Huang, Wenwen, et al.
Publicado: (2022)

Validated UPLC-MS/MS method for quantification of fruquintinib in rat plasma and its application to pharmacokinetic study
por: Mei, Yi-Bin, et al.
Publicado: (2019)

Simultaneous Quantification of Four Phenylethanoid Glycosides in Rat Plasma by UPLC-MS/MS and Its Application to a Pharmacokinetic Study of Acanthus Ilicifolius Herb
por: Zhang, Mengqi, et al.
Publicado: (2019)

Pharmacokinetic and Metabolism Studies of 12-Riboside-Pseudoginsengenin DQ by UPLC-MS/MS and UPLC-QTOF-MS(E)
por: Wang, Zhenzhou, et al.
Publicado: (2018)

Pharmacokinetics and UPLC-MS/MS of Delsoline in Mouse Whole Blood
por: Shao, Lingjiu, et al.
Publicado: (2018)

Comparative Pharmacokinetics of Cinobufacini Capsule and Injection by UPLC-MS/MS
por: Li, Ming, et al.
Publicado: (2022)

Investigation of preclinical pharmacokinetics of N-demethylsinomenine, a potential novel analgesic candidate, using an UPLC-MS/MS quantification method
por: Yu, Lulu, et al.
Publicado: (2023)

Three New Ursane-Type Triterpenoids from the Stems of Saprosma merrillii
por: Zhang, Dashuai, et al.
Publicado: (2013)

UPLC–MS/MS assay for quantification of an inhibitor of kinases (Foretinib) in plasma: Application to a pharmacokinetic study in rats
por: Ezzeldin, Essam, et al.
Publicado: (2020)

Development of a UPLC-MS/MS Method for the Quantification of VS-5584 and Its Application in Pharmacokinetic Studies in Rats
por: Zhou, Chunling, et al.
Publicado: (2020)

Development and validation of an UPLC-ESI-MS/MS method for quantification of duvelisib in plasma: application to pharmacokinetic study in rats
por: Darwish, Ibrahim A., et al.
Publicado: (2023)

Development of a robust UPLC-MS/MS method for the quantification of riluzole in human plasma and its application in pharmacokinetics
por: Sun, Zhuo, et al.
Publicado: (2023)

Quantitation of Apremilast in Beagle Dogs Plasma by UPLC-MS-MS and Its Application to Pharmacokinetic Studies
por: Xiong, Wei, et al.
Publicado: (2021)

Simultaneous Determination of Six Uncaria Alkaloids in Mouse Blood by UPLC–MS/MS and Its Application in Pharmacokinetics and Bioavailability
por: Chen, Lianguo, et al.
Publicado: (2020)

Simultaneous Determination of Celecoxib, Dezocine and Dexmedetomidine in Beagle Plasma Using UPLC-MS/MS Method and the Application in Pharmacokinetics
por: Hu, Jie, et al.
Publicado: (2021)

Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat Determined by UPLC-MS/MS
por: Chang, Li-Wen, et al.
Publicado: (2013)

Effects of Xuesaitong on the Pharmacokinetics of Losartan: An In Vivo UPLC-MS/MS Study
por: Ma, Weina, et al.
Publicado: (2019)

Validated UPLC-MS/MS method for the quantification of dasatinib in plasma: Application to pharmacokinetic interaction studies with nutraceuticals in Wistar rats
por: Maher, Hadir M., et al.
Publicado: (2018)

A New UPLC-MS/MS Method Validated for Quantification of Jervine in Rat Plasma and the Study of Its Pharmacokinetics in Rats
por: Chen, Lianguo, et al.
Publicado: (2019)

Rapid and Simultaneous Quantification of Five Quinolizidine Alkaloids in Lupinus angustifolius L. and Its Processed Foods by UPLC–MS/MS
por: Hwang, In Min, et al.
Publicado: (2020)

Simultaneous determination of indapamide, perindopril and perindoprilat in human plasma or whole blood by UPLC-MS/MS and its pharmacokinetic application
por: Tao, Yi, et al.
Publicado: (2018)

Pharmacokinetic Comparisons of Different Combinations of Yigan Jiangzhi Formula in Rats: Simultaneous Determination of Fourteen Components by UPLC-MS/MS
por: Wang, Yang, et al.
Publicado: (2020)

Simultaneous Determination of Parecoxib and Its Metabolite Valdecoxib Concentrations in Beagle Plasma by UPLC-MS/MS and Application for Pharmacokinetics Study
por: Li, Shuang-long, et al.
Publicado: (2020)

Simultaneous Determination of Three Bioactive Constituents from Bletilla striata by UPLC-MS/MS and Application of the Technique to Pharmacokinetic Analyses
por: Chen, Hao, et al.
Publicado: (2019)

UPLC/Q-TOF MS-Based Metabolomics and qRT-PCR in Enzyme Gene Screening with Key Role in Triterpenoid Saponin Biosynthesis of Polygala tenuifolia
por: Zhang, Fusheng, et al.
Publicado: (2014)

Pharmacokinetics and Bioavailability Study of Tubeimoside I in ICR Mice by UPLC-MS/MS
por: Chen, Lianguo, et al.
Publicado: (2018)

The Effect of Posaconazole and Isavuconazole on the Pharmacokinetics of Erdafitinib in Beagle Dogs by UPLC-MS/MS
por: Ruan, Lan-hong, et al.
Publicado: (2021)

Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach
por: Liu, Pei, et al.
Publicado: (2022)

Pharmacokinetics of Herb-Drug Interactions of Plumbagin and Tazemetostat in Rats by UPLC-MS/MS
por: Li, Heng, et al.
Publicado: (2022)

Inhibitory effect of Schisandrin on the pharmacokinetics of poziotinib in vivo and in vitro by UPLC‐MS/MS
por: Wang, Shuanghu, et al.
Publicado: (2023)

Development and Validation a UPLC-MS/MS Method for Quantification of Pentoxifylline in Beagle Plasma: Application for Pharmacokinetic Study of Food Effect
por: Xu, Yuxiang, et al.
Publicado: (2023)

Development and validation of a high throughput UPLC–MS/MS method for simultaneous quantification of esomeprazole, rabeprazole and levosulpiride in human plasma()
por: Chunduri, Raja Haranadha Babu, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_3q75rvaqvgh1dlhh2arg8flmqr