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Collagen-based three-dimensional culture microenvironment promotes epithelial to mesenchymal transition and drug resistance of human ovarian cancer in vitro

Ovarian cancer (OvCa) is a leading cause of mortality from gynecologic malignancy due to its disseminated peritoneal metastasis. The tumor microenvironment dominates epithelial–mesenchymal transition (EMT) development and impacts cancer metastasis as well as mediates drug resistance. Tumour cell int...

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Detalles Bibliográficos
Autores principales: Liu, Ming, Zhang, Xiuzhen, Long, Canling, Xu, Hong, Cheng, Xu, Chang, Jingjie, Zhang, Chengzhao, Zhang, Chenghong, Wang, Xiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078576/
https://www.ncbi.nlm.nih.gov/pubmed/35539845
http://dx.doi.org/10.1039/c7ra13742g