UV-mediated hydrophosphinylation of unactivated alkenes with phosphinates under batch and flow conditions

A UV-mediated hydrophosphinylation of unactivated alkenes with H-phosphinates and hypophosphorous acid under radical free conditions is presented. The reaction affords selectively a large number of structurally diverse organophosphorous compounds in moderate to good yields under mild reaction condit...

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Autores principales: Gelat, Fabien, Roger, Maxime, Penverne, Christophe, Mazzad, Ahmed, Rolando, Christian, Chausset-Boissarie, Laëtitia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078595/
https://www.ncbi.nlm.nih.gov/pubmed/35542039
http://dx.doi.org/10.1039/c7ra12977g
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author Gelat, Fabien
Roger, Maxime
Penverne, Christophe
Mazzad, Ahmed
Rolando, Christian
Chausset-Boissarie, Laëtitia
author_facet Gelat, Fabien
Roger, Maxime
Penverne, Christophe
Mazzad, Ahmed
Rolando, Christian
Chausset-Boissarie, Laëtitia
author_sort Gelat, Fabien
collection PubMed
description A UV-mediated hydrophosphinylation of unactivated alkenes with H-phosphinates and hypophosphorous acid under radical free conditions is presented. The reaction affords selectively a large number of structurally diverse organophosphorous compounds in moderate to good yields under mild reaction conditions in the presence of an organic sensitizer as catalyst irradiated by UV-A LEDs. Furthermore, the high yielding hydrophosphinylation in continuous flow is disclosed.
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spelling pubmed-90785952022-05-09 UV-mediated hydrophosphinylation of unactivated alkenes with phosphinates under batch and flow conditions Gelat, Fabien Roger, Maxime Penverne, Christophe Mazzad, Ahmed Rolando, Christian Chausset-Boissarie, Laëtitia RSC Adv Chemistry A UV-mediated hydrophosphinylation of unactivated alkenes with H-phosphinates and hypophosphorous acid under radical free conditions is presented. The reaction affords selectively a large number of structurally diverse organophosphorous compounds in moderate to good yields under mild reaction conditions in the presence of an organic sensitizer as catalyst irradiated by UV-A LEDs. Furthermore, the high yielding hydrophosphinylation in continuous flow is disclosed. The Royal Society of Chemistry 2018-02-23 /pmc/articles/PMC9078595/ /pubmed/35542039 http://dx.doi.org/10.1039/c7ra12977g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Gelat, Fabien
Roger, Maxime
Penverne, Christophe
Mazzad, Ahmed
Rolando, Christian
Chausset-Boissarie, Laëtitia
UV-mediated hydrophosphinylation of unactivated alkenes with phosphinates under batch and flow conditions
title UV-mediated hydrophosphinylation of unactivated alkenes with phosphinates under batch and flow conditions
title_full UV-mediated hydrophosphinylation of unactivated alkenes with phosphinates under batch and flow conditions
title_fullStr UV-mediated hydrophosphinylation of unactivated alkenes with phosphinates under batch and flow conditions
title_full_unstemmed UV-mediated hydrophosphinylation of unactivated alkenes with phosphinates under batch and flow conditions
title_short UV-mediated hydrophosphinylation of unactivated alkenes with phosphinates under batch and flow conditions
title_sort uv-mediated hydrophosphinylation of unactivated alkenes with phosphinates under batch and flow conditions
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078595/
https://www.ncbi.nlm.nih.gov/pubmed/35542039
http://dx.doi.org/10.1039/c7ra12977g
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AT mazzadahmed uvmediatedhydrophosphinylationofunactivatedalkeneswithphosphinatesunderbatchandflowconditions
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