White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation

A cationic conjugated polyelectrolyte (CPE) PPET3 with a poly(p-phenylene ethynylene terthiophene) backbone and quaternary ammonium side chains was designed and synthesized. It serves as an efficient photosensitizer for photodynamic therapy under white light irradiation and induces cell death throug...

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Detalles Bibliográficos
Autores principales: Liang, Jiamei, Wu, Pan, Tan, Chunyan, Jiang, Yuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078657/
https://www.ncbi.nlm.nih.gov/pubmed/35541876
http://dx.doi.org/10.1039/c8ra00774h
Descripción
Sumario:A cationic conjugated polyelectrolyte (CPE) PPET3 with a poly(p-phenylene ethynylene terthiophene) backbone and quaternary ammonium side chains was designed and synthesized. It serves as an efficient photosensitizer for photodynamic therapy under white light irradiation and induces cell death through the mitochondrial apoptosis pathway.

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