White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation

A cationic conjugated polyelectrolyte (CPE) PPET3 with a poly(p-phenylene ethynylene terthiophene) backbone and quaternary ammonium side chains was designed and synthesized. It serves as an efficient photosensitizer for photodynamic therapy under white light irradiation and induces cell death throug...

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Detalles Bibliográficos
Autores principales: Liang, Jiamei, Wu, Pan, Tan, Chunyan, Jiang, Yuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078657/
https://www.ncbi.nlm.nih.gov/pubmed/35541876
http://dx.doi.org/10.1039/c8ra00774h
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author Liang, Jiamei
Wu, Pan
Tan, Chunyan
Jiang, Yuyang
author_facet Liang, Jiamei
Wu, Pan
Tan, Chunyan
Jiang, Yuyang
author_sort Liang, Jiamei
collection PubMed
description A cationic conjugated polyelectrolyte (CPE) PPET3 with a poly(p-phenylene ethynylene terthiophene) backbone and quaternary ammonium side chains was designed and synthesized. It serves as an efficient photosensitizer for photodynamic therapy under white light irradiation and induces cell death through the mitochondrial apoptosis pathway.
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spelling pubmed-90786572022-05-09 White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation Liang, Jiamei Wu, Pan Tan, Chunyan Jiang, Yuyang RSC Adv Chemistry A cationic conjugated polyelectrolyte (CPE) PPET3 with a poly(p-phenylene ethynylene terthiophene) backbone and quaternary ammonium side chains was designed and synthesized. It serves as an efficient photosensitizer for photodynamic therapy under white light irradiation and induces cell death through the mitochondrial apoptosis pathway. The Royal Society of Chemistry 2018-03-01 /pmc/articles/PMC9078657/ /pubmed/35541876 http://dx.doi.org/10.1039/c8ra00774h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Liang, Jiamei
Wu, Pan
Tan, Chunyan
Jiang, Yuyang
White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation
title White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation
title_full White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation
title_fullStr White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation
title_full_unstemmed White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation
title_short White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation
title_sort white light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078657/
https://www.ncbi.nlm.nih.gov/pubmed/35541876
http://dx.doi.org/10.1039/c8ra00774h
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AT wupan whitelightinducedcellapoptosisbyaconjugatedpolyelectrolytethroughsingletoxygengeneration
AT tanchunyan whitelightinducedcellapoptosisbyaconjugatedpolyelectrolytethroughsingletoxygengeneration
AT jiangyuyang whitelightinducedcellapoptosisbyaconjugatedpolyelectrolytethroughsingletoxygengeneration

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