A novel fluorescent probe for imaging the process of HOCl oxidation and Cys/Hcy reduction in living cells

A new on-off-on fluorescent probe, CMOS, based on coumarin was developed to detect the process of hypochlorous acid (HOCl) oxidative stress and cysteine/homocysteine (Cys/Hcy) reduction. The probe exhibited a fast response, good sensitivity and selectivity. Moreover, it was applied for monitoring th...

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Detalles Bibliográficos
Autores principales: Liu, Zhen, Li, Guoping, Wang, Yana, Li, Jiulong, Mi, Yang, Guo, Linna, Xu, Wenjian, Zou, Dapeng, Li, Tiesheng, Wu, Yangjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078674/
https://www.ncbi.nlm.nih.gov/pubmed/35541868
http://dx.doi.org/10.1039/c7ra13419c
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author Liu, Zhen
Li, Guoping
Wang, Yana
Li, Jiulong
Mi, Yang
Guo, Linna
Xu, Wenjian
Zou, Dapeng
Li, Tiesheng
Wu, Yangjie
author_facet Liu, Zhen
Li, Guoping
Wang, Yana
Li, Jiulong
Mi, Yang
Guo, Linna
Xu, Wenjian
Zou, Dapeng
Li, Tiesheng
Wu, Yangjie
author_sort Liu, Zhen
collection PubMed
description A new on-off-on fluorescent probe, CMOS, based on coumarin was developed to detect the process of hypochlorous acid (HOCl) oxidative stress and cysteine/homocysteine (Cys/Hcy) reduction. The probe exhibited a fast response, good sensitivity and selectivity. Moreover, it was applied for monitoring the redox process in living cells.
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spelling pubmed-90786742022-05-09 A novel fluorescent probe for imaging the process of HOCl oxidation and Cys/Hcy reduction in living cells Liu, Zhen Li, Guoping Wang, Yana Li, Jiulong Mi, Yang Guo, Linna Xu, Wenjian Zou, Dapeng Li, Tiesheng Wu, Yangjie RSC Adv Chemistry A new on-off-on fluorescent probe, CMOS, based on coumarin was developed to detect the process of hypochlorous acid (HOCl) oxidative stress and cysteine/homocysteine (Cys/Hcy) reduction. The probe exhibited a fast response, good sensitivity and selectivity. Moreover, it was applied for monitoring the redox process in living cells. The Royal Society of Chemistry 2018-03-05 /pmc/articles/PMC9078674/ /pubmed/35541868 http://dx.doi.org/10.1039/c7ra13419c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Liu, Zhen
Li, Guoping
Wang, Yana
Li, Jiulong
Mi, Yang
Guo, Linna
Xu, Wenjian
Zou, Dapeng
Li, Tiesheng
Wu, Yangjie
A novel fluorescent probe for imaging the process of HOCl oxidation and Cys/Hcy reduction in living cells
title A novel fluorescent probe for imaging the process of HOCl oxidation and Cys/Hcy reduction in living cells
title_full A novel fluorescent probe for imaging the process of HOCl oxidation and Cys/Hcy reduction in living cells
title_fullStr A novel fluorescent probe for imaging the process of HOCl oxidation and Cys/Hcy reduction in living cells
title_full_unstemmed A novel fluorescent probe for imaging the process of HOCl oxidation and Cys/Hcy reduction in living cells
title_short A novel fluorescent probe for imaging the process of HOCl oxidation and Cys/Hcy reduction in living cells
title_sort novel fluorescent probe for imaging the process of hocl oxidation and cys/hcy reduction in living cells
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078674/
https://www.ncbi.nlm.nih.gov/pubmed/35541868
http://dx.doi.org/10.1039/c7ra13419c
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