Convenient and efficient synthesis of functionalized unsymmetrical Z-alkenyl disulfanes

We developed a simple and efficient method for the synthesis of functionalized unsymmetrical Z-alkenyl disulfanes under mild conditions in moderate to good yields. The designed method is based on the reaction of Z-alkenyl thiotosylates with thiols in the presence of base. The developed method allows...

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Detalles Bibliográficos
Autores principales: Musiejuk, M., Doroszuk, J., Witt, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078699/
https://www.ncbi.nlm.nih.gov/pubmed/35540801
http://dx.doi.org/10.1039/c8ra00659h
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author Musiejuk, M.
Doroszuk, J.
Witt, D.
author_facet Musiejuk, M.
Doroszuk, J.
Witt, D.
author_sort Musiejuk, M.
collection PubMed
description We developed a simple and efficient method for the synthesis of functionalized unsymmetrical Z-alkenyl disulfanes under mild conditions in moderate to good yields. The designed method is based on the reaction of Z-alkenyl thiotosylates with thiols in the presence of base. The developed method allows the preparation of unsymmetrical Z-alkenyl disulfanes bearing additional hydroxy, carboxy, or amino functionalities.
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spelling pubmed-90786992022-05-09 Convenient and efficient synthesis of functionalized unsymmetrical Z-alkenyl disulfanes Musiejuk, M. Doroszuk, J. Witt, D. RSC Adv Chemistry We developed a simple and efficient method for the synthesis of functionalized unsymmetrical Z-alkenyl disulfanes under mild conditions in moderate to good yields. The designed method is based on the reaction of Z-alkenyl thiotosylates with thiols in the presence of base. The developed method allows the preparation of unsymmetrical Z-alkenyl disulfanes bearing additional hydroxy, carboxy, or amino functionalities. The Royal Society of Chemistry 2018-03-07 /pmc/articles/PMC9078699/ /pubmed/35540801 http://dx.doi.org/10.1039/c8ra00659h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Musiejuk, M.
Doroszuk, J.
Witt, D.
Convenient and efficient synthesis of functionalized unsymmetrical Z-alkenyl disulfanes
title Convenient and efficient synthesis of functionalized unsymmetrical Z-alkenyl disulfanes
title_full Convenient and efficient synthesis of functionalized unsymmetrical Z-alkenyl disulfanes
title_fullStr Convenient and efficient synthesis of functionalized unsymmetrical Z-alkenyl disulfanes
title_full_unstemmed Convenient and efficient synthesis of functionalized unsymmetrical Z-alkenyl disulfanes
title_short Convenient and efficient synthesis of functionalized unsymmetrical Z-alkenyl disulfanes
title_sort convenient and efficient synthesis of functionalized unsymmetrical z-alkenyl disulfanes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078699/
https://www.ncbi.nlm.nih.gov/pubmed/35540801
http://dx.doi.org/10.1039/c8ra00659h
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AT doroszukj convenientandefficientsynthesisoffunctionalizedunsymmetricalzalkenyldisulfanes
AT wittd convenientandefficientsynthesisoffunctionalizedunsymmetricalzalkenyldisulfanes

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