Drifts in N-Linked Glycosylation Result in ADCC Potency Variation of Perjeta® from August 2020 to October 2021 in China

The proposed biosimilar candidate needs to demonstrate biosimilarity with reference products, and the quality target product profile and biosimilarity assessment criteria are prerequisite, which should be based on extensive characterization of the reference products. In this study, 13 lots of China-...

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Detalles Bibliográficos
Autores principales: Yao, Bing, Zhang, Di, Cao, Weirong, Yang, Gaoqiang, Li, Wenbin, Hui, Xiwu, Ouyang, Pingkai, Chen, Guoguang, Liu, Boning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078787/
https://www.ncbi.nlm.nih.gov/pubmed/35535043
http://dx.doi.org/10.1155/2022/7868391

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