Open Search-Based Proteomics Reveals Widespread Tryptophan Modifications Associated with Hypoxia in Lung Cancer

The tryptophan residue has a large hydrophobic surface that plays a unique role in the folded protein conformation and functions. Tryptophan modifications are presumably to be readily detected in proteins due to the vulnerability of the indole structure to electrophilic attacks. In this study, we re...

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Detalles Bibliográficos
Autores principales: Chen, Jinfeng, Zhang, Lei, Sun, Zhao, Li, Hongyi, Li, Jingyi, Xue, Xinli, Zhu, Qingqing, Dong, Bowen, Wang, Yuanyuan, Yang, Yang, Dong, Yongqiang, Guo, Guangyu, Jiang, Hongqiang, Zhang, An, Zhang, Guoqing, Hou, Zhichao, Li, Xiangnan, Yang, Jing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078843/
https://www.ncbi.nlm.nih.gov/pubmed/35535361
http://dx.doi.org/10.1155/2022/2590198

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