Cargando…

Tissue metabolomic profiling to reveal the therapeutic mechanism of reduning injection on LPS-induced acute lung injury rats

Acute lung injury (ALI) is a severe respiratory disease. To date, no medical interventions have been proven effective in improving the outcome. Reduning injection (RDN) showed a potential effect in the therapy of ALI. However, seldom does research concern the holistic pharmacological mechanisms of R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Zhili, Wang, Yanmin, Lang, Lang, Ma, Shuping, Zhao, Longshan, Xiao, Wei, Wang, Yanjuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078858/ https://www.ncbi.nlm.nih.gov/pubmed/35540831 http://dx.doi.org/10.1039/c7ra13123b

Ejemplares similares

Reduning Injection prevents carrageenan-induced inflammation in rats by serum and urine metabolomics analysis
por: Gao, Xia, et al.
Publicado: (2022)

Two new terpenoids from Reduning Injection
por: Li, Hai-bo, et al.
Publicado: (2020)

Assessing the Anti-inflammatory Mechanism of Reduning Injection by Network Pharmacology
por: Xie, Fuda, et al.
Publicado: (2020)

Pathway as a Pharmacological Target for Herbal Medicines: An Investigation from Reduning Injection
por: Liu, Jianling, et al.
Publicado: (2015)

Identification of the Allergenic Ingredients in Reduning Injection by Ultrafiltration and High-Performance Liquid Chromatography
por: Wang, Fang, et al.
Publicado: (2016)

A novel systems pharmacology model for herbal medicine injection: a case using reduning injection
por: Yang, Haixing, et al.
Publicado: (2014)

The Activity-Integrated Method for Quality Assessment of Reduning Injection by On-Line DPPH-CE-DAD
por: Chang, Yan-xu, et al.
Publicado: (2014)

Reduning Injection versus Neuraminidase Inhibitors in the Treatment of Influenza: A Systematic Review and Meta-Analysis
por: Zhao, Guo-zhen, et al.
Publicado: (2022)

Active Ingredients of Reduning Injection Maintain High Potency against SARS-CoV-2 Variants
por: Xiao, Zhen, et al.
Publicado: (2022)

Reduning injection combined with western medicine for pneumonia: A protocol for systematic review and meta-analysis
por: Cao, Chenggang, et al.
Publicado: (2020)

Reduning Attenuates LPS-Induced Human Unmilical Vein Endothelial Cells (HUVECs) Apoptosis Through PI3K-AKT Signaling Pathway
por: Wang, Ziyi, et al.
Publicado: (2022)

Pharmacokinetic Study of Coadministration with Cefuroxime Sodium for Injection Influencing ReDuNing Injection-Derived Seven Phytochemicals and Nine Metabolites in Rats
por: Zhao, Qiulong, et al.
Publicado: (2022)

Feasibility and mechanism analysis of Reduning in the prevention of sepsis-induced pulmonary fibrosis
por: Wang, Ziyi, et al.
Publicado: (2022)

Metabolomic profiling to reveal the therapeutic potency of Posidonia oceanica nanoparticles in diabetic rats
por: Ammar, Naglaa M., et al.
Publicado: (2021)

The curative effect of Reduning injection combined with Xuanfeibaidu formula on COVID-19: A protocol for systematic review and meta-analysis
por: Wang, Yunze, et al.
Publicado: (2020)

Anti-inflammatory effects of Reduning Injection (热毒宁注射液) on lipopolysaccharide-induced acute lung injury of rats
por: Tang, Lu-ping, et al.
Publicado: (2014)

Dissecting the novel mechanism of reduning injection in treating Coronavirus Disease 2019 (COVID-19) based on network pharmacology and experimental verification
por: Jia, Shanshan, et al.
Publicado: (2021)

Identification of the cytochrome P450 enzymes involved in the oxidative metabolism of trantinterol using ultra high-performance liquid chromatography coupled with tandem mass spectrometry
por: Li, Kunjie, et al.
Publicado: (2018)

Multiscale Modeling of Drug-induced Effects of ReDuNing Injection on Human Disease: From Drug Molecules to Clinical Symptoms of Disease
por: Luo, Fang, et al.
Publicado: (2015)

Efficacy and safety of ReDuNing injection as a treatment for COVID-19 and its inhibitory effect against SARS-CoV-2
por: Ma, Qinhai, et al.
Publicado: (2021)

Reduning alleviates sepsis-induced acute lung injury by reducing apoptosis of pulmonary microvascular endothelial cells
por: Wang, Ziyi, et al.
Publicado: (2023)

Tissue metabolomics study to reveal the toxicity of a traditional Tibetan medicine ‘Renqing Changjue’ in rats
por: Xu, Can, et al.
Publicado: (2018)

Clinical Observation of Reduning Combined with Recombinant Human Interferon α-2b in the Treatment of Children with Viral Pneumonia
por: Li, Zhuangzhuang, et al.
Publicado: (2022)

The synergistic Reduning and cefmetazole sodium treatment of severe pneumonia is mediated by the AhR-Src-STAT3 pathway
por: Luo, Shanjun, et al.
Publicado: (2022)

NMR-based metabolomic profiling of Peganum harmala L. reveals dynamic variations between different growth stages
por: Li, Yinping, et al.
Publicado: (2018)

Metabolomic profiling of matured coconut water during post-harvest storage revealed discrimination and distinct changes in metabolites
por: Chen, Weijun, et al.
Publicado: (2018)

Global metabolomic profiling of trastuzumab resistant gastric cancer cells reveals major metabolic pathways and metabolic signatures based on UHPLC-Q exactive-MS/MS
por: Liu, Wenhu, et al.
Publicado: (2019)

Serum metabolomic alterations in multiple myeloma revealed by targeted and untargeted metabolomics approaches: a pilot study
por: Chanukuppa, Venkatesh, et al.
Publicado: (2019)

Targeted metabolomic profiling in rat tissues reveals sex differences
por: Ruoppolo, Margherita, et al.
Publicado: (2018)

Transcriptomic and Metabolomic Analyses of the Effects of Exogenous Trehalose on Heat Tolerance in Wheat
por: Luo, Yin, et al.
Publicado: (2022)

Urinary metabolomics reveals the therapeutic effect of HuangQi Injections in cisplatin-induced nephrotoxic rats
por: Li, Chang-Yin, et al.
Publicado: (2017)

Metabolome profiling and molecular docking analysis revealed the metabolic differences and potential pharmacological mechanisms of the inflorescence and succulent stem of Cistanche deserticola
por: Sun, Xiao, et al.
Publicado: (2021)

Comparative metabolomic profiling of Cupriavidus necator B-4383 revealed production of cupriachelin siderophores, one with activity against Cryptococcus neoformans
por: Ahmed, Mohammed M. A., et al.
Publicado: (2023)

Global-Scale Metabolomic Profiling of Human Hair for Simultaneous Monitoring of Endogenous Metabolome, Short- and Long-Term Exposome
por: Chen, Ying, et al.
Publicado: (2021)

Integration of Metabolomics and Transcriptomics Reveals the Therapeutic Mechanism Underlying Paeoniflorin for the Treatment of Allergic Asthma
por: Shou, Qiyang, et al.
Publicado: (2019)

Metabolomics profiling reveals berberine-inhibited inflammatory response in human gingival fibroblasts by regulating the LPS-induced apoptosis signaling pathway
por: Zhang, Ying, et al.
Publicado: (2022)

Biomimetic enzyme barrier for preventing intestine-derived LPS induced diseases
por: Zhao, Cheng, et al.
Publicado: (2020)

Protective effects of silibinin on LPS-induced inflammation in human periodontal ligament cells
por: Meng, Di, et al.
Publicado: (2022)

A UPLC-MS-based metabolomics approach to reveal the attenuation mechanism of Caowu compatibility with Yunnan Baiyao
por: Ren, Jun-ling, et al.
Publicado: (2019)

Serum metabolomics strategy for understanding the therapeutic effects of Yin-Chen-Hao-Tang against Yanghuang syndrome
por: Liu, Xing-yuan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_t8o6v6sm3iraqldl3qfscj467j