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Discovery of novel inhibitors of RNA silencing suppressor P19 based on virtual screening

To control plant viruses, viral RNA silencing suppressors are important drug targets due to their key roles in interfering antiviral RNA silencing. Here we have presented a strategy, combining virtual and experimental screening, to discover the inhibitors of viral suppressor. By docking 157 026 comp...

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Detalles Bibliográficos
Autores principales: Hu, Fan, Lei, Rong, Deng, Yu-Fang, Wang, Jun, Li, Gui-Fen, Wang, Chao-Nan, Li, Zhi-Hong, Zhu, Shui-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078884/
https://www.ncbi.nlm.nih.gov/pubmed/35540466
http://dx.doi.org/10.1039/c8ra01311j