Cargando…
Discovery of novel inhibitors of RNA silencing suppressor P19 based on virtual screening
To control plant viruses, viral RNA silencing suppressors are important drug targets due to their key roles in interfering antiviral RNA silencing. Here we have presented a strategy, combining virtual and experimental screening, to discover the inhibitors of viral suppressor. By docking 157 026 comp...
Autores principales: | Hu, Fan, Lei, Rong, Deng, Yu-Fang, Wang, Jun, Li, Gui-Fen, Wang, Chao-Nan, Li, Zhi-Hong, Zhu, Shui-Fang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078884/ https://www.ncbi.nlm.nih.gov/pubmed/35540466 http://dx.doi.org/10.1039/c8ra01311j |
Ejemplares similares
-
Discovery of human TyrRS inhibitors by structure-based virtual screening, structural optimization, and bioassays
por: Huang, Shenzhen, et al.
Publicado: (2019) -
Discovery of New α-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation
por: Liu, Shan-Kui, et al.
Publicado: (2021) -
Combination of Virtual Screening Protocol by in Silico toward the Discovery of Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors
por: Fu, Ying, et al.
Publicado: (2018) -
Virtual screening–based discovery of AI-2 quorum sensing inhibitors that interact with an allosteric hydrophobic site of LsrK and their functional evaluation
por: Shi, Qianqian, et al.
Publicado: (2023) -
Discovery of Cobimetinib as a novel A-FABP inhibitor using machine learning and molecular docking-based virtual screening
por: Yang, Shilun, et al.
Publicado: (2022)