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Friedel–Crafts alkylation reaction with fluorinated alcohols as hydrogen-bond donors and solvents
An effective and clean FC alkylation of indoles and electron-rich arenes with β-nitroalkenes in HFIP was reported. The desired products are formed rapidly in excellent yields under mild conditions without the need for any additional catalysts or reagents. Further, this methodology can be applied to...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078892/ https://www.ncbi.nlm.nih.gov/pubmed/35540471 http://dx.doi.org/10.1039/c8ra01397g |