Polymer encapsulation of anticancer silver–N-heterocyclic carbene complexes

Amphiphilic block copolymers have been developed for the encapsulation of organometallic drugs. silver–N-heterocyclic carbene complexes have shown significant promise as anticancer and antibacterial compounds, and have been studied as the payload in these carriers. Simple modification of the N-heter...

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Detalles Bibliográficos
Autores principales: Mohamed, H. A., Khuphe, M., Boardman, S. J., Shepherd, S., Phillips, R. M., Thornton, P. D., Willans, C. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078921/
https://www.ncbi.nlm.nih.gov/pubmed/35540495
http://dx.doi.org/10.1039/c8ra00450a
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author Mohamed, H. A.
Khuphe, M.
Boardman, S. J.
Shepherd, S.
Phillips, R. M.
Thornton, P. D.
Willans, C. E.
author_facet Mohamed, H. A.
Khuphe, M.
Boardman, S. J.
Shepherd, S.
Phillips, R. M.
Thornton, P. D.
Willans, C. E.
author_sort Mohamed, H. A.
collection PubMed
description Amphiphilic block copolymers have been developed for the encapsulation of organometallic drugs. silver–N-heterocyclic carbene complexes have shown significant promise as anticancer and antibacterial compounds, and have been studied as the payload in these carriers. Simple modification of the N-heterocyclic carbene ligand structure enables solubility properties and interaction with the polymer to be tuned.
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spelling pubmed-90789212022-05-09 Polymer encapsulation of anticancer silver–N-heterocyclic carbene complexes Mohamed, H. A. Khuphe, M. Boardman, S. J. Shepherd, S. Phillips, R. M. Thornton, P. D. Willans, C. E. RSC Adv Chemistry Amphiphilic block copolymers have been developed for the encapsulation of organometallic drugs. silver–N-heterocyclic carbene complexes have shown significant promise as anticancer and antibacterial compounds, and have been studied as the payload in these carriers. Simple modification of the N-heterocyclic carbene ligand structure enables solubility properties and interaction with the polymer to be tuned. The Royal Society of Chemistry 2018-03-15 /pmc/articles/PMC9078921/ /pubmed/35540495 http://dx.doi.org/10.1039/c8ra00450a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Mohamed, H. A.
Khuphe, M.
Boardman, S. J.
Shepherd, S.
Phillips, R. M.
Thornton, P. D.
Willans, C. E.
Polymer encapsulation of anticancer silver–N-heterocyclic carbene complexes
title Polymer encapsulation of anticancer silver–N-heterocyclic carbene complexes
title_full Polymer encapsulation of anticancer silver–N-heterocyclic carbene complexes
title_fullStr Polymer encapsulation of anticancer silver–N-heterocyclic carbene complexes
title_full_unstemmed Polymer encapsulation of anticancer silver–N-heterocyclic carbene complexes
title_short Polymer encapsulation of anticancer silver–N-heterocyclic carbene complexes
title_sort polymer encapsulation of anticancer silver–n-heterocyclic carbene complexes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078921/
https://www.ncbi.nlm.nih.gov/pubmed/35540495
http://dx.doi.org/10.1039/c8ra00450a
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