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Bicyclo[2.2.1]heptane containing N,N′-diarylsquaramide CXCR2 selective antagonists as anti-cancer metastasis agents

CXCR1 and CXCR2 are CXC chemokine receptors (CXCRs), corresponding to cytokines of the CXC chemokine family. CXCR2 was found to be 77% homologous to CXCR1. Antagonism of the chemokine receptor CXCR2 has been proposed as a new strategy for the treatment of metastatic cancer. In order to find a CXCR2...

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Detalles Bibliográficos
Autores principales:	Che, Jin-Xin, Wang, Zhi-Long, Dong, Xiao-Wu, Hu, You-Hong, Xie, Xin, Hu, Yong-Zhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078949/ https://www.ncbi.nlm.nih.gov/pubmed/35541503 http://dx.doi.org/10.1039/c8ra01806e

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