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Enhanced osteoarthritis therapy by nanoengineered mesenchymal stem cells using biomimetic CuS nanoparticles loaded with plasmid DNA encoding TGF-β1
Mesenchymal stem cells (MSCs) therapy shows the potential benefits to relieve clinical symptoms of osteoarthritis (OA), but it is uncertain if it can repair articular cartilage lesions — the main pathology of OA. Here, we prepared biomimetic cupper sulfide@phosphatidylcholine (CuS@PC) nanoparticles...
Autores principales: | Cai, Yu, Wu, Cuixi, Ou, Qianhua, Zeng, Muhui, Xue, Song, Chen, Jieli, Lu, Yao, Ding, Changhai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079106/ https://www.ncbi.nlm.nih.gov/pubmed/35574050 http://dx.doi.org/10.1016/j.bioactmat.2022.04.021 |
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