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A novel glutathione-triggered theranostic prodrug for anticancer and imaging in living cells

A novel theranostic prodrug was designed and synthesized by conjugating a naphthalimide derivative with vitamin D(2)via a disulfide linker. The prodrug featured a highly selective detection process for glutathione (GSH) and showed a red-shifted fluorescence within 30 min. Notably, it also exhibited...

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Detalles Bibliográficos
Autores principales: Zhang, Hengrui, Fang, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079131/
https://www.ncbi.nlm.nih.gov/pubmed/35542771
http://dx.doi.org/10.1039/c8ra00271a

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