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A novel glutathione-triggered theranostic prodrug for anticancer and imaging in living cells
A novel theranostic prodrug was designed and synthesized by conjugating a naphthalimide derivative with vitamin D(2)via a disulfide linker. The prodrug featured a highly selective detection process for glutathione (GSH) and showed a red-shifted fluorescence within 30 min. Notably, it also exhibited...
Autores principales: | Zhang, Hengrui, Fang, Zhijie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079131/ https://www.ncbi.nlm.nih.gov/pubmed/35542771 http://dx.doi.org/10.1039/c8ra00271a |
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