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Allosteric regulation by membranes and hydrophobic subsites in phospholipase A(2) enzymes determine their substrate specificity
Lipids play critical roles in several major chronic diseases of our times, including those that involve inflammatory sequelae such as metabolic syndrome including obesity, insulin sensitivity, and cardiovascular diseases. However, defining the substrate specificity of enzymes of lipid metabolism is...
Autor principal: | Dennis, Edward A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079178/ https://www.ncbi.nlm.nih.gov/pubmed/35358512 http://dx.doi.org/10.1016/j.jbc.2022.101873 |
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