Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines

A simple and efficient metal-free arylation of imidazo[1,2-a]pyridines at the C-3 position with arylhydrazine has been achieved at room temperature under ambient air conditions. Various 2,3-disubstituted imidazopyridines and imidazothiazoles were synthesized with high yields. The present methodology...

Descripción completa

Detalles Bibliográficos
Autores principales: Jana, Sourav, Samanta, Sadhanendu, Bagdi, Avik K., Shirinian, Valerii Z., Hajra, Alakananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079221/
https://www.ncbi.nlm.nih.gov/pubmed/35539413
http://dx.doi.org/10.1039/c8ra01474d
_version_ 1784702514345541632
author Jana, Sourav
Samanta, Sadhanendu
Bagdi, Avik K.
Shirinian, Valerii Z.
Hajra, Alakananda
author_facet Jana, Sourav
Samanta, Sadhanendu
Bagdi, Avik K.
Shirinian, Valerii Z.
Hajra, Alakananda
author_sort Jana, Sourav
collection PubMed
description A simple and efficient metal-free arylation of imidazo[1,2-a]pyridines at the C-3 position with arylhydrazine has been achieved at room temperature under ambient air conditions. Various 2,3-disubstituted imidazopyridines and imidazothiazoles were synthesized with high yields. The present methodology demonstrates the usefulness of commercially available aryl hydrazine as an arylating agent.
format Online
Article
Text
id pubmed-9079221
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90792212022-05-09 Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines Jana, Sourav Samanta, Sadhanendu Bagdi, Avik K. Shirinian, Valerii Z. Hajra, Alakananda RSC Adv Chemistry A simple and efficient metal-free arylation of imidazo[1,2-a]pyridines at the C-3 position with arylhydrazine has been achieved at room temperature under ambient air conditions. Various 2,3-disubstituted imidazopyridines and imidazothiazoles were synthesized with high yields. The present methodology demonstrates the usefulness of commercially available aryl hydrazine as an arylating agent. The Royal Society of Chemistry 2018-04-03 /pmc/articles/PMC9079221/ /pubmed/35539413 http://dx.doi.org/10.1039/c8ra01474d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Jana, Sourav
Samanta, Sadhanendu
Bagdi, Avik K.
Shirinian, Valerii Z.
Hajra, Alakananda
Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines
title Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines
title_full Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines
title_fullStr Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines
title_full_unstemmed Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines
title_short Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines
title_sort metal-free c–h arylation of imidazoheterocycles with aryl hydrazines
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079221/
https://www.ncbi.nlm.nih.gov/pubmed/35539413
http://dx.doi.org/10.1039/c8ra01474d
work_keys_str_mv AT janasourav metalfreecharylationofimidazoheterocycleswitharylhydrazines
AT samantasadhanendu metalfreecharylationofimidazoheterocycleswitharylhydrazines
AT bagdiavikk metalfreecharylationofimidazoheterocycleswitharylhydrazines
AT shirinianvaleriiz metalfreecharylationofimidazoheterocycleswitharylhydrazines
AT hajraalakananda metalfreecharylationofimidazoheterocycleswitharylhydrazines

Ejemplares similares