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Fabrication and characterization of a novel self-assembling micelle based on chitosan cross-linked pectin–doxorubicin conjugates macromolecular pro-drug for targeted cancer therapy

Cancer is one of the leading causes of morbidity and mortality worldwide. Doxorubicin is one of the most effective anticancer drugs approved by FDA. However, like all the other anticancer drugs, the efficacy of DOX is associated with high systemic toxicity to healthy tissues. In this study, chitosan...

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Detalles Bibliográficos
Autores principales: Li, Zhi-Ping, Jiang, Ming-Chao, Chen, Bo, Gao, Pei, Yang, Sa, Liu, Yu-Feng, Ye, Peng-Ju, He, Dong-Xiu, Huang, Hong-Lin, Yu, Cui-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079223/
https://www.ncbi.nlm.nih.gov/pubmed/35539373
http://dx.doi.org/10.1039/c8ra01403e