A case of immunoglobulin G4-Related disease with pleural effusion, requiring exclusion of tuberculous pleurisy

Immunoglobulin G4 (IgG4)-related pleurisy is a rare type of IgG4-related disease. We present the case of a 69-year-old woman with left pleural effusion and elevated adenosine deaminase levels. Initially, tuberculous pleuritis was suspected; however, the bacterial cultures and polymerase chain reacti...

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Detalles Bibliográficos
Autores principales: Doita, Susumu, Tamura, Tomoki, Baba, Takahiro, Oomori, Hiroki, Nishii, Kazuya, Nakanishi, Masamoto, Kuyama, Shoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079228/
https://www.ncbi.nlm.nih.gov/pubmed/35540692
http://dx.doi.org/10.1016/j.rmcr.2022.101654
Descripción
Sumario:Immunoglobulin G4 (IgG4)-related pleurisy is a rare type of IgG4-related disease. We present the case of a 69-year-old woman with left pleural effusion and elevated adenosine deaminase levels. Initially, tuberculous pleuritis was suspected; however, the bacterial cultures and polymerase chain reaction test results for tuberculosis were negative. Thoracoscopic pleural biopsy revealed dense lymphocytic infiltrates with large numbers of IgG4-positive plasma cells. The ratio of IgG4-positive to IgG-positive plasma cells exceeded 40%. The patient was diagnosed with IgG4-related disease.

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