Adsorption of tetrakis(4-sulfophenyl)porphyrin onto liposomal surfaces composed of neutral diacylphosphatidylcholine and release by cyclodextrin

Anionic tetrakis(4-sulfophenyl)porphyrin (TPPS) interacts with liposomal surfaces composed of neutral diacylphosphatidylcholine at high lipid concentrations. TPPS interacted with liposomal surfaces through four contact points. The association constant was obtained to be 9.0 × 10(5) M(−4). TPPS was p...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Yuki, Nakaya, Toshimi, Kakigi, Tomoyuki, Sugikawa, Kouta, Ikeda, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079261/
https://www.ncbi.nlm.nih.gov/pubmed/35539372
http://dx.doi.org/10.1039/c8ra01411f
Descripción
Sumario:Anionic tetrakis(4-sulfophenyl)porphyrin (TPPS) interacts with liposomal surfaces composed of neutral diacylphosphatidylcholine at high lipid concentrations. TPPS interacted with liposomal surfaces through four contact points. The association constant was obtained to be 9.0 × 10(5) M(−4). TPPS was peeled off the liposomal surfaces by the addition of cyclodextrin.

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