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Enzymatic synthesis of nucleoside analogues from uridines and vinyl esters in a continuous-flow microreactor
We achieved the effective controllable regioselective acylation of the primary hydroxyl group of uridine derivatives catalyzed by Lipase TL IM from Thermomyces lanuginosus with excellent conversion and regioselectivity. Various reaction parameters were studied. These regioselective acylations perfor...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079605/ https://www.ncbi.nlm.nih.gov/pubmed/35541271 http://dx.doi.org/10.1039/c8ra01030g |