Cobalt-catalyzed C(sp(3))–H/C(sp(2))–H oxidative coupling between alkanes and benzamides

A direct cobalt-catalyzed oxidative coupling between C(sp(2))–H in unactivated benzamides and C(sp(3))–H in simple alkanes, ethers and toluene derivatives was explored. This protocol achieves direct C–C formation without using alkyl or aryl halide surrogates and exhibits high practicality with ample...

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Detalles Bibliográficos
Autores principales: Li, Shuangjie, Wang, Bao, Dong, Guangyu, Li, Chunpu, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079668/
https://www.ncbi.nlm.nih.gov/pubmed/35542514
http://dx.doi.org/10.1039/c8ra01377b
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author Li, Shuangjie
Wang, Bao
Dong, Guangyu
Li, Chunpu
Liu, Hong
author_facet Li, Shuangjie
Wang, Bao
Dong, Guangyu
Li, Chunpu
Liu, Hong
author_sort Li, Shuangjie
collection PubMed
description A direct cobalt-catalyzed oxidative coupling between C(sp(2))–H in unactivated benzamides and C(sp(3))–H in simple alkanes, ethers and toluene derivatives was explored. This protocol achieves direct C–C formation without using alkyl or aryl halide surrogates and exhibits high practicality with ample substrate scope. The method provides a new way to construct linear and five- or six-membered ring moieties in bioactive molecules.
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spelling pubmed-90796682022-05-09 Cobalt-catalyzed C(sp(3))–H/C(sp(2))–H oxidative coupling between alkanes and benzamides Li, Shuangjie Wang, Bao Dong, Guangyu Li, Chunpu Liu, Hong RSC Adv Chemistry A direct cobalt-catalyzed oxidative coupling between C(sp(2))–H in unactivated benzamides and C(sp(3))–H in simple alkanes, ethers and toluene derivatives was explored. This protocol achieves direct C–C formation without using alkyl or aryl halide surrogates and exhibits high practicality with ample substrate scope. The method provides a new way to construct linear and five- or six-membered ring moieties in bioactive molecules. The Royal Society of Chemistry 2018-04-10 /pmc/articles/PMC9079668/ /pubmed/35542514 http://dx.doi.org/10.1039/c8ra01377b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Li, Shuangjie
Wang, Bao
Dong, Guangyu
Li, Chunpu
Liu, Hong
Cobalt-catalyzed C(sp(3))–H/C(sp(2))–H oxidative coupling between alkanes and benzamides
title Cobalt-catalyzed C(sp(3))–H/C(sp(2))–H oxidative coupling between alkanes and benzamides
title_full Cobalt-catalyzed C(sp(3))–H/C(sp(2))–H oxidative coupling between alkanes and benzamides
title_fullStr Cobalt-catalyzed C(sp(3))–H/C(sp(2))–H oxidative coupling between alkanes and benzamides
title_full_unstemmed Cobalt-catalyzed C(sp(3))–H/C(sp(2))–H oxidative coupling between alkanes and benzamides
title_short Cobalt-catalyzed C(sp(3))–H/C(sp(2))–H oxidative coupling between alkanes and benzamides
title_sort cobalt-catalyzed c(sp(3))–h/c(sp(2))–h oxidative coupling between alkanes and benzamides
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079668/
https://www.ncbi.nlm.nih.gov/pubmed/35542514
http://dx.doi.org/10.1039/c8ra01377b
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AT dongguangyu cobaltcatalyzedcsp3hcsp2hoxidativecouplingbetweenalkanesandbenzamides
AT lichunpu cobaltcatalyzedcsp3hcsp2hoxidativecouplingbetweenalkanesandbenzamides
AT liuhong cobaltcatalyzedcsp3hcsp2hoxidativecouplingbetweenalkanesandbenzamides

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