Pharmacological ascorbate improves the response to platinum-based chemotherapy in advanced stage non-small cell lung cancer

PURPOSE: Platinum-based chemotherapy with or without immunotherapy is the mainstay of treatment for advanced stage non-small cell lung cancer (NSCLC) lacking a molecular driver alteration. Pre-clinical studies have reported that pharmacological ascorbate (P-AscH-) enhances NSCLC response to platinum...

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Detalles Bibliográficos
Autores principales: Furqan, Muhammad, Abu-Hejleh, Taher, Stephens, Laura M., Hartwig, Stacey M., Mott, Sarah L., Pulliam, Casey F., Petronek, Michael, Henrich, John B., Fath, Melissa A., Houtman, Jon C., Varga, Steven M., Bodeker, Kellie L., Bossler, Aaron D., Bellizzi, Andrew M., Zhang, Jun, Monga, Varun, Mani, Hariharasudan, Ivanovic, Marina, Smith, Brian J., Byrne, Margaret M., Zeitler, William, Wagner, Brett A., Buettner, Garry R., Cullen, Joseph J., Buatti, John M., Spitz, Douglas R., Allen, Bryan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079696/
https://www.ncbi.nlm.nih.gov/pubmed/35525024
http://dx.doi.org/10.1016/j.redox.2022.102318

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