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An optimized procedure for direct access to 1H-indazole-3-carboxaldehyde derivatives by nitrosation of indoles

Indazole derivatives are currently drawing more and more attention in medicinal chemistry as kinase inhibitors. 1H-indazole-3-carboxaldehydes are key intermediates to access to a variety of polyfunctionalized 3-substituted indazoles. We report here a general access to this motif, based on the nitros...

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Detalles Bibliográficos
Autores principales: Chevalier, Arnaud, Ouahrouch, Abdelaaziz, Arnaud, Alexandre, Gallavardin, Thibault, Franck, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079728/
https://www.ncbi.nlm.nih.gov/pubmed/35542511
http://dx.doi.org/10.1039/c8ra01546e

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