Retracted Article: Chrysin attenuates myocardial ischemia–reperfusion injury by inhibiting myocardial inflammation

The aim of this study was to investigate the effects of chrysin (CH) on myocardial ischemia–reperfusion injury. Cytokines were reduced by CH in coronary artery occlusion-induced rats and also in H9C2 cells. The ST segment was also restored by CH. Triphenyltetrazolium chloride (TTC) staining and path...

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Autores principales: Wu, Jingguo, Xun, Nan, Yang, Yang, Zeng, Lijin, Li, Zhenyu, Yang, Wen, Liang, Yanbing, Tang, Hao, Ma, Zhongfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079803/
https://www.ncbi.nlm.nih.gov/pubmed/35539337
http://dx.doi.org/10.1039/c8ra00590g
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author Wu, Jingguo
Xun, Nan
Yang, Yang
Zeng, Lijin
Li, Zhenyu
Yang, Wen
Liang, Yanbing
Tang, Hao
Ma, Zhongfu
author_facet Wu, Jingguo
Xun, Nan
Yang, Yang
Zeng, Lijin
Li, Zhenyu
Yang, Wen
Liang, Yanbing
Tang, Hao
Ma, Zhongfu
author_sort Wu, Jingguo
collection PubMed
description The aim of this study was to investigate the effects of chrysin (CH) on myocardial ischemia–reperfusion injury. Cytokines were reduced by CH in coronary artery occlusion-induced rats and also in H9C2 cells. The ST segment was also restored by CH. Triphenyltetrazolium chloride (TTC) staining and pathological analysis showed that CH could alleviate myocardial injury. Results in H9C2 cells showed that CH improved heart injury in hypoxia/reoxygenation (H/R) of H9C2 cells. In addition, the expressions of the HMGB1-related inflammation pathway in rats and H9C2 cells were significantly decreased by CH. The present study shows the protective effects of CH on myocardial injury via inflammation.
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spelling pubmed-90798032022-05-09 Retracted Article: Chrysin attenuates myocardial ischemia–reperfusion injury by inhibiting myocardial inflammation Wu, Jingguo Xun, Nan Yang, Yang Zeng, Lijin Li, Zhenyu Yang, Wen Liang, Yanbing Tang, Hao Ma, Zhongfu RSC Adv Chemistry The aim of this study was to investigate the effects of chrysin (CH) on myocardial ischemia–reperfusion injury. Cytokines were reduced by CH in coronary artery occlusion-induced rats and also in H9C2 cells. The ST segment was also restored by CH. Triphenyltetrazolium chloride (TTC) staining and pathological analysis showed that CH could alleviate myocardial injury. Results in H9C2 cells showed that CH improved heart injury in hypoxia/reoxygenation (H/R) of H9C2 cells. In addition, the expressions of the HMGB1-related inflammation pathway in rats and H9C2 cells were significantly decreased by CH. The present study shows the protective effects of CH on myocardial injury via inflammation. The Royal Society of Chemistry 2018-04-12 /pmc/articles/PMC9079803/ /pubmed/35539337 http://dx.doi.org/10.1039/c8ra00590g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Wu, Jingguo
Xun, Nan
Yang, Yang
Zeng, Lijin
Li, Zhenyu
Yang, Wen
Liang, Yanbing
Tang, Hao
Ma, Zhongfu
Retracted Article: Chrysin attenuates myocardial ischemia–reperfusion injury by inhibiting myocardial inflammation
title Retracted Article: Chrysin attenuates myocardial ischemia–reperfusion injury by inhibiting myocardial inflammation
title_full Retracted Article: Chrysin attenuates myocardial ischemia–reperfusion injury by inhibiting myocardial inflammation
title_fullStr Retracted Article: Chrysin attenuates myocardial ischemia–reperfusion injury by inhibiting myocardial inflammation
title_full_unstemmed Retracted Article: Chrysin attenuates myocardial ischemia–reperfusion injury by inhibiting myocardial inflammation
title_short Retracted Article: Chrysin attenuates myocardial ischemia–reperfusion injury by inhibiting myocardial inflammation
title_sort retracted article: chrysin attenuates myocardial ischemia–reperfusion injury by inhibiting myocardial inflammation
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079803/
https://www.ncbi.nlm.nih.gov/pubmed/35539337
http://dx.doi.org/10.1039/c8ra00590g
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