Insights into the molecular mechanism underlying CD4-dependency and neutralization sensitivity of HIV-1: a comparative molecular dynamics study on gp120s from isolates with different phenotypes

The envelope (Env) of HIV-1 plays critical roles in viral infection and immune evasion. Although structures of prefusion Env have been determined and phenotypes relevant to the CD4 dependency and the neutralization sensitivity for various HIV-1 isolates have been identified, the detailed structural...

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Detalles Bibliográficos
Autores principales: Li, Yi, Deng, Lei, Ai, Shi-Meng, Sang, Peng, Yang, Jing, Xia, Yuan-Lin, Zhang, Zhi-Bi, Fu, Yun-Xin, Liu, Shu-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079880/
https://www.ncbi.nlm.nih.gov/pubmed/35540760
http://dx.doi.org/10.1039/c8ra00425k

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